Cardiac Functions and Clinical Outcomes in Patients with Chronic Liver Disease: A Cohort Study

After IEC clearance and CTRI registration, this prospective observational study will be conducted. Chronic liver disease patients advised cardiac evaluation at Kasturba Hospital, Manipal, will be enrolled in this study. Cases are selected if willing to give informed consent.12 lead ECGs will be recorded. ECG Gated 4D Echocardiography, along with Conventional and Strain echocardiography (layer-specific strain)) will be performed and recorded. Strain echocardiographic analysis will be performed offline with the already available recorded echo images and stored for future reference. LVEF, RV parameters, strain, and strain rate will be measured at baseline. Standard views will be taken with the patient lying in the left lateral decubitus position. Standard views were recorded and stored, i.e., the parasternal long axis and short axis at three levels of LV and the apical 4,5,3 and 2 chamber views. LVEF measurements will be taken using M mode and Simpson’s method. These images will be stored for offline analysis of strain. The study will be continued and performed at six months of follow-up. A reminder call will be given to the patients for follow-up. The follow-up data will be collected, and all the parameters will be reassessed at six months of Follow-up. Till the study duration, all the clinical outcomes will be followed up