Epidemiology of Carbapenemase-producing Bacteria in a Swiss Tertiary Care Hospital

Recruiting

• Conditions: Infections With CPB

• Registration Number: NCT04098133
• Lead Sponsor: University Hospital, Basel, Switzerland

Brief Summary

This retrospective and prospective study is to investigate the incidence of Carbapenemase-producing bacteria (CPB) at the University Hospital Basel, the time to detection of CPB and to initiation of infection control measures, the risk factors associated with carriage of CPB, type and duration of previously administrated antibiotic medication, antibiotic treatment, as well as to assess the outcomes of the affected patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-08-22
• Study First Submitted: 2019-09-17
• Study First Submitted QC: 2019-09-17
• Study First Posted: 2019-09-23
• Status Verified: 2024-12
• Last Update Submitted: 2024-12-12
• Last Update Posted: 2024-12-13
• Primary Completion: 2029-06-30
• Study Completion: 2029-06-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Patients with detection of carbapenemase-producing bacteria from January 1st , 2008 until December 31st , 2028

Exclusion Criteria

• Patients with documented refusal of subsequent use of their data

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
incidence of CPB at the University Hospital Basel (number)	from January 1st , 2008 until December 31st, 2028	incidence of CPB at the University Hospital Basel (number)

Secondary Outcome Measures

Name	Time	Method
time to adequate treatment in patients with CPB infections	from January 1st , 2008 until December 31st, 2028	time to adequate treatment in patients with CPB infections
cure from infection	from January 1st , 2008 until December 31st, 2028	cure from infection
cause-specific mortality (number)	from January 1st , 2008 until December 31st, 2028	cause-specific mortality (number)
time to initiation of infection control measures	from January 1st , 2008 until December 31st, 2028	time to initiation of infection control measures
all-cause mortality (number)	from January 1st , 2008 until December 31st, 2028	all-cause mortality (number)
time to detection of CPB (days)	from January 1st , 2008 until December 31st, 2028	time to detection of CPB (days)
presence of established risk factors for CPB	from January 1st , 2008 until December 31st, 2028	presence of established risk factors for CPB
length of hospital stay (days)	from January 1st , 2008 until December 31st, 2028	length of hospital stay (days)
discharge destination	from January 1st , 2008 until December 31st, 2028	discharge destination

Trial Locations

Locations (1)

Division of Infectious Diseases and Hospital Epidemiology; 🇨🇭 Basel, Switzerland