Understanding the Relationship Between Inflammation and Insulin Resistance in the Adipose Tissue
Not Applicable
Completed
- Conditions
- ObesityInsulin Resistance
- Registration Number
- NCT02378077
- Lead Sponsor
- Mayo Clinic
- Brief Summary
This study is being done to better understand the relationship between inflammation and insulin resistance in your Adipose (fat) Tissue .
- Detailed Description
This study is being done to determine whether eosinophils (a type of white blood cell) play an important role in human fat metabolism and inflammation.
This study is being done to determine if fish oil supplement could play a role in reducing inflammation and improving insulin sensitivity in your fat tissue.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 28
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Eosinophil content in adipose tissue baseline Eosinophils number will be measured by flow cytometry in subcutaneous and visceral fat of lean vs obese, non-diabetic volunteers
- Secondary Outcome Measures
Name Time Method Relationship between eosinophils content and body mass index (BMI) baseline Measure as a linear regression between BMI (kg/m2) and eosinophils number in the fat
Trial Locations
- Locations (1)
Mayo Clinic in Arizona
🇺🇸Scottsdale, Arizona, United States
Mayo Clinic in Arizona🇺🇸Scottsdale, Arizona, United States