Assessment of Acute Kidney Injury as a Risk Factor for Myocardial Injury After Non Cardiac Surgery in Critical Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Acute Kidney Injury (AKI)
- Sponsor
- South Egypt Cancer Institute
- Enrollment
- 240
- Locations
- 1
- Primary Endpoint
- Creatinine level
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
The incidence of acute kidney injury (AKI) postoperatively has been identified to be 21.6% in adults and 18.3% in hospitalized individuals. Surgery-related AKI is a severe complication that is related not only to short-term complications as increases in mortality rate and development of cardiac complications but also with complications on long term, such as development of chronic kidney disease. A better understanding of the mechanism of this hypthesis will lead to better management of this complication.
Detailed Description
A randomized blinded prospective study included 206patients who the candidate for major surgery at South Egypt Cancer Institute, Assiut University, Assiut, Egypt. From April 2018 till April 2019, a detailed history and careful examination, routine laboratory investigations were done, Baseline ECG was recorded 24hours before surgery and 48hours postoperative at ICU.
Investigators
Alaa Ali M. Elzohry
Lecturer of Anesthesia, ICU and Pain Relief, South Egypt Cancer Institute, Assiut University, Egypt
South Egypt Cancer Institute
Eligibility Criteria
Inclusion Criteria
- •patients who were candidates for major non cardiac surgery
Exclusion Criteria
- •chronic cardiac diseases (myocardial ischemia, heart failure), Active severe infection, pregnancy, chronic kidney disease
Outcomes
Primary Outcomes
Creatinine level
Time Frame: every 12 hours
Creatinine twice the baseline and urine output of fewer than 0.5 ml/kg per hour for 12 hours