A human study for evaluating effectiveness and safety of Theracurmin CR-033P on antioxidant capacity
- Conditions
- Not Applicable
- Registration Number
- KCT0003322
- Lead Sponsor
- Chungnam National University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 80
1) Subject who voluntarily agree to participate and signs informed consent form
2) Men and women aged 20 to under 65.
3) fulfill the current workout habits or diet habits during the study.
1) Impossible to performa treadmill activity
2) Continuous intensive workout (more than 1.5 hours a week) within 3 months from the first visit
3) Chronic smoker (= 10 cigarettes / day)
4) Intake more than 420 g of pure alcohol a week (Soju 7bottles/week, 1bottle/day) or an alcoholic
5) Recommended Food Score > 36
6) BMI<18.5 or BMI=30
7) Controlling body weight or have changed of body weight more than 4kg within 4 weeks before the first visit
8) Comply the following categories
- Have following diseases or taking relevant medicines: Systemic infection, severe cardiovascular disease (hypertension, stroke), digestive system disease, kidney disease, thyroid disease, autoimmune disease, malignant tumor, multisystem failure, inflammatory bowel disease, uncontrolled meantal illness, HIV
- Those who have received organ transplants and bone marrow transplants
- Those who taking steroids, antibiotics, and anti-inflammatory drugs (NSAIDs) continuously within 1 month before the first visit
- Therapeutic uses of coumadin, aspirin, or other medications that influence hemostasis within three weeks of the first visit.
9) Continuous consumption of health functional food(Coenzyme Q10,antioxidantsmultivitamin etc), and medicinal herbs within 1 months before the first visit
10) Donated blood within 1 month before the first visit
11) Known hypersensitivity to study product or any ingredient in study product
12) Pregnant or lactating women
13) Participation in other human study within 1 month before the first visit
14) Any condition that the principal investigator believes may put the subjects at under risk
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method antioxidant enzyme activity (Superoxide dismutase, catalase activity etc), oxidative stress marker (Thiobarbituric acid reactive substances, 8-hydroxydeoxyguanosine etc)
- Secondary Outcome Measures
Name Time Method Inflammation markers (tumor necrosis factor-a, interleukin-6 etc)