A human study to evaluate safety and effective dose of Phellinus baumii extract complex on platelet aggregation response and blood flow in healthy subjects given a dietary lipid challenge: a randomized, double-blind, placebo-controlled, cross-over study
- Conditions
- Diseases of the circulatory system
- Registration Number
- KCT0001193
- Lead Sponsor
- Ewha Womans University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 56
Subects who informed consent
Healthy subjects (30-65 years)
BMI > 35kg/m2
body weight fluctuation of 10% or more in the past 8weeks
excessive activity
takes hormone therapy (female)
excessive smoker
drinking alcohol more than 140g/week
platelet function disorder
taking anti-platelet medication (aspirin, non-steroidal anti-inflammatory drugs)
cardiovascular or haematological disorders, insulin resistance, diagnosed non-insulin dependent diabetes
disease (Cardiovascular disease, heart failure, myocardial infarction, cerebrovascular disease, arteriosclerosis, diabetes, thyroid abnormality, ulcer, gastric bleeding, infectious diseases, systemic inflammatory diseases, acute inflammation, malignancy, renal disease, renal function, liver disease, lung disease, blood coagulopathy)
take oriental medicine or other medicine during test period continuously
subjects who have hypersensitivity about test material
take fuctional foods continuously in the 4 weeks
participate other human study in the 12 weeks
pregnat woman or lactating woman
subjects who unsuiable about this study
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Platelet aggregation test
- Secondary Outcome Measures
Name Time Method Blood flow;Lipids