The effect of dexmedetomidine in reducing pain after jaw surgery

Not Applicable

• Conditions: Fracture of mandible.; Fracture of mandible; S02.6

• Registration Number: IRCT20220819055746N1
• Lead Sponsor: Tabriz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 November 2022

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Age above 18 years
Candidate for mandibular surgery
Consent to participate in the study

Exclusion Criteria

History of allergy to dexmedetomidine
Multi-trauma patients
Addiction to drugs and psychoactive substances
History of taking antidepressants
History of previous mandible, maxilla and cheek surgery during the last three months
Patients diagnosed with rheumatoid arthritis
Patients with kidney and liver diseases
Dialysis patients
Patients receiving anticoagulant drugs
Patients with a history of systemic infections
Patients with hemostatic disorders

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain intensity. Timepoint: during recovery, the first, second, fourth, sixth, twelfth and twenty-fourth hours after discharge from recovery. Method of measurement: Visual Analogue Scale.;The amount of using opioid. Timepoint: during recovery, the first, second, fourth, sixth, twelfth and twenty-fourth hours after discharge from recovery. Method of measurement: The amount of pain during recovery is measured in the first, second, fourth, sixth, twelfth and twenty-fourth hours after discharge from recovery. If the Visual Analogue Scale is higher than 5, pethidine (Exir-Iran company) at the rate of 1 mg/kg will be injected intramuscularly. After four hours, in case of recurrence of pain, the pethidine injection will be repeated at the rate of 1mg/kg. The number of times the patient needs pethidine in twenty-four hours will be recorded.