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Global Network Implementation of Helping Babies Breathe (HBB)

Not Applicable
Completed
Conditions
Perinatal Mortality
Interventions
Other: HBB/ENC supplies
Behavioral: HBB/ENC Training and Equipment
Registration Number
NCT01681017
Lead Sponsor
NICHD Global Network for Women's and Children's Health
Brief Summary

The primary purpose of this pre-post evaluation is to test the impact on perinatal mortality (fresh stillbirths or early neonatal deaths) among births \> 1500g of training birth attendants at health facilities in the Helping Babies Breathe (HBB) and Essential Newborn Care (ENC) curricula. These facilities are located within clusters in the Global Network for Women's and Children's Health Research sites in Belgaum and Nagpur, India, and Eldoret, Kenya.

Detailed Description

Helping Babies Breathe (HBB) is a training program designed to resuscitate neonates regardless of where they were born. HBB was developed by the American Academy of Pediatrics (AAP), the NICHD's Global Network for Women's and Children's Health (GN), the Laerdal Foundation and their global partners. The HBB program was developed based upon the experience and results of an earlier Neonatal Resuscitation Program and the GN's FIRST BREATH randomized control trial.

The goal of the study is to test the impact of training birth attendants at selected health facilities in the Helping Babies Breathe (HBB) and Essential Newborn Care (ENC) curricula upon perinatal mortality (fresh stillbirths and early neonatal deaths), among births of ≥1500g. The training will take place in three GN sites, Kenya, and Nagpur and Belgaum, India. The study facilities serve the population in identified study clusters, defined geographic areas which participate in the GN's Maternal Newborn Health (MNH) Registry. In addition to measuring perinatal mortality rate pre and post training, the study will also assess resuscitation skills among the birth attendants as a result of the training. Quality Improvement activities are planned to ensure the integrity of the training, maintenance and availability of resuscitation equipment and skills maintenance.

The GN MNH Registry (NCT 01073475) was established in 2008 and includes all pregnancies and neonatal outcomes in defined geographic clusters. The primary outcome for the pre-post HBB evaluation study will be calculated using all delivery data from the GN MNH Registry for participating clusters during the defined study period.

The pre-post HBB evaluation will include the following key activities:

1. Selection of Master Trainers, Facilitators, and Learners

2. Country-level training of Master Trainers in the HBB and ENC curricula

3. Facility-level training of birth attendants in the HBB and ENC curricula

4. Periodic re-training of birth attendants in the HBB and ENC curricula

5. Quality improvement activities:

* Regular observation of deliveries in participating study health facilities

* Unannounced observation of deliveries (or HBB skills using a neonatal simulator if no deliveries are available)

* Resuscitation debriefings

* Perinatal Death audits

* Daily bag and mask ventilation practice

* Drills to practice emergency drills

* Daily check of cleanliness and availability of resuscitation equipment.

The HBB Master Trainers (MT), Facilitators, and Learners will be evaluated at several points during the implementation of the training program and quality improvement activities.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
70704
Inclusion Criteria
  • Facilities:

    • at least 60 deliveries per year;
    • ability to provide 24-hour coverage, 7 days per week in the delivery ward; and
    • minimum perinatal mortality rate of 30 per 1000 deliveries in the reference period.

Master Trainers (MT)

  • Experienced teachers and content experts in neonatal resuscitation
  • Trained and/or experienced in education
  • Dedication to learner-focused education
  • Able to give informed consent

Facilitators

  • Experienced in teaching Learners in small groups
  • Experienced in care of newborns
  • Demonstrated understanding of course content
  • Aptitude for teaching
  • Able to give informed consent

Learners

  • Skilled birth attendants with clearly defined responsibilities for attending deliveries at participating facilities
  • Able to give informed consent
Exclusion Criteria
  • If a facility, master trainer, facilitator, or learner does not meet the above inclusion criteria they are excluded from the study.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
FacilitiesHBB/ENC suppliesHave appropriate staff trained in HBB and have HBB equipment provided
Master TrainersHBB/ENC Training and EquipmentReceive appropriate HBB training
FacilitatorsHBB/ENC Training and EquipmentReceive appropriate HBB training
LearnersHBB/ENC Training and EquipmentReceive appropriate HBB training
Primary Outcome Measures
NameTimeMethod
Perinatal MortalityPerinatal mortality data collected at 6 weeks post-delivery. Comparison will include the pre-intervention period of 12 months and the post-intervention period of 12 months.

The difference in the rate of perinatal mortality (fresh stillbirth or neonatal death prior to 7 days) among births ≥1500g, pre versus post implementation of an integrated package of HBB and ENC training and equipment (referred to as HBB/ENC training and equipment). This measure will be calculated using delivery data from the Global Network's Maternal Newborn Health Registry for participating clusters.

Secondary Outcome Measures
NameTimeMethod
Facility-based perinatal mortalityPerinatal mortality data collected at 6 weeks post-delivery. Comparison will include the pre-intervention period of 12 months and the post-intervention period of 12 months.

The difference in the rate of facility-based perinatal mortality, among births ≥1500g pre versus post implementation of HBB/ENC training and equipment.

Delivery room checklist scoreObservations conducted on a monthly basis.

The difference in scores on delivery room checklist (in facilities with \> 100 deliveries/year)

Facility deliveriesData collected at 6 weeks post-delivery. Comparison will include the pre-intervention period of 12 months and the post-intervention period of 12 months.

The difference in the proportion of facility deliveries pre versus post HBB/ENC training.

Health seeking behaviorData collected at 6 weeks post-delivery. Comparison will include the pre-intervention period of 12 months and the post-intervention period of 12 months.

The difference in the proportion of health seeking behavior pre versus post HBB/ENC training.

Retention of resuscitation knowledge and skillsAssessments completed at initial training and refresher training.

The difference pre versus post intervention in mean scores on a multiple choice test of resuscitation knowledge, observed skills in bag and mask ventilation (BMV), and OSCE A and OSCE B scenarios.

Number of neonatal resuscitationsResuscitation data collected at 6 weeks post-delivery.

The difference in the number of neonatal resuscitations, among births ≥1500g with bag and mask in participating facilities pre versus post HBB/ENC training and equipment.

Asphyxia related perinatal mortalityPerinatal mortality data collected at 6 weeks post-delivery. Comparison will include the pre-intervention period of 12 months and the post-intervention period of 12 months.

The difference in the rate of asphyxia related perinatal mortality, among births ≥1500g pre versus post HBB/ENC training.

Very early newborn death (within 1 day of birth)Data collected at 6 weeks post-delivery. Comparison will include the pre-intervention period of 12 months and the post-intervention period of 12 months.

The difference in very early newborn death (within 1 day of birth) pre versus post HBB/ENC training.

Trial Locations

Locations (3)

Moi University School of Medicine

🇰🇪

Eldoret, Kenya

Lata Medical Research Foundation

🇮🇳

Nagpur, India

Jawaharlal Nehru Medical College

🇮🇳

Belgaum, India

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