effect of the combination of green lipped mussel, curcumin and ribus nigrum (supplement Synofit) on quality of life and pain in patients with osteoarthritis of the knee
Phase 2
Completed
- Conditions
- arthritis of the kneegonarthritis10023213
- Registration Number
- NL-OMON39393
- Lead Sponsor
- Ziekenhuisvoorzieningen Gelderse Vallei
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 62
Inclusion Criteria
- patients with clinical and radiological osteoarthritis of the knee (uni-and bilateral)
- voluntary participation
Exclusion Criteria
- patients with arthritis of the knee with an operation indication
- comborbidity: rheumatoid arthritis, polyarthritis
- patient who use medication as: methotrexate and systemic corticosteroids
- arthritis of the hip at the same side (referred pain)
- patients who use analgetica stronger than NSAIDs (f.e. Tramadol, Opioids)
- pregnancy
- allergic or sensitivity for ingredients of Synofit
- patient who use Synofit before
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>during the first consultation and at 6, 12 and 18 weeks, the pain scores by the<br /><br>VAS-scale and quality of life by the KOOS-score are taken. Another outcome is<br /><br>extra pain medication within one of the study periods of suppletion.</p><br>
- Secondary Outcome Measures
Name Time Method <p>side-effects<br /><br>compliance</p><br>