Mussel with fucoidan as a supplemented superfood for adults with prediabetes and joint pai

Not Applicable

Completed

• Conditions: prediabetes; joint pain; Metabolic and Endocrine - Diabetes; Musculoskeletal - Other muscular and skeletal disorders; Anaesthesiology - Pain management

• Registration Number: ACTRN12621000413820
• Lead Sponsor: niversity of Auckland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-04-15
• Study Completion: 2023-02-17
• Last Update Posted: 21 August 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 146

Inclusion Criteria

Chinese participants with Prediabetes defined by recent HbA1c between 39-49 mmol/mol, and lasting knee or hip joint pain (e.g. hip or knee pain) for the last three months or longer

Exclusion Criteria

Diabetes, Known or suspected seafood (fish and shellfish) allergy, Currently taking a green-lipped mussel supplement, Previous joint replacement surgery, or planning this within the next six months, Pregnant or breastfeeding, or intending to become pregnant within the next six months, Previous bariatric surgery, Conditions which may influence body weight regulation (e.g. malabsorption, thyroid disorders), Taking any glucose-lowering medications, systemic steroids, or blood thinners, Thalassemia, asthma, gout, liver disease, kidney disease, Planning major changes to physical activity within the next six months, Significant weight loss or weight gain within the last six months, Fear of needles or giving blood, and No access to a smartphone, tablet, or Internet.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blood serum samples will be used to measure insulin and glucose and insulin resistance, defined by the homeostasis model of assessment (HOMA) values, will be derived those measurements. [Baseline (day 0), and 100 days after the trial starting date];Change in Joint pain measured by Western Ontario and McMaster Universities Arthritis (WOMAC) Index pain subscale-B (WOMAC-B)[Baseline (day 0) and 100 days after the trial starting date]