Effect of Fish Oil Supplement on Pregnancy Outcome in Women with a History of High-risk Pregnancy

Not Applicable

Conditions: Increase of blood pressure during current pregnancy.
Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

Registration Number: IRCT20100701004281N3

Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: Female

Target Recruitment: 200

Inclusion Criteria

Iranian race
Age between 18 and 40 years
Second pregnancy and after that
History of problems such as preterm delivery; intrauterine growth retardation; preeclampsia; induced gestational hypertension in previous pregnancy
The first visit to a medical center before the 16th week of pregnancy

Exclusion Criteria

Threat of miscarriage and placental abruption (bleeding) in the current pregnancy
Cervical cerclage
Having cardiovascular disease; kidney disease and lack of urinary tract infections; polyhydramnios; chronic lung disease; liver disease; hepatitis of any type; hyper and hypothyroidism; overt diabetes or gestational diabetes in previous pregnancies; diagnosis or suspicion of severe fetal abnormalities or hydrops in the current pregnancy
Substance abuse, alcohol and smoking; regular consumption of fish oil or nonsteroidal anti-inflammatory agents or other medications
Allergy to fish products
Lack of desire to take pill and irregular visit

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ewborn Weight. Timepoint: At birth time. Method of measurement: By means of newborns scale into gram.;Apgar score in the first and fifth minutes. Timepoint: At birth time. Method of measurement: Observation and physical examination.

Secondary Outcome Measures

Name	Time	Method
Childbirth before 37 weeks. Timepoint: At the time of hospitalization. Method of measurement: Estimation of gestational age.;Increase of blood pressure. Timepoint: From the 16th week of pregnancy on prenatal visits. Method of measurement: By Blood pressure control device.;Mode of delivery. Timepoint: at birth time. Method of measurement: observation.