The Impact of Fish Oil Supplementation on The Efficacy and Side Effects of Low-dose Isotretinoin in Treatment of Moderate-to-severe Acne Vulgaris Compared to Low-dose Isotretinoin Monotherapy.
Phase 3
Recruiting
- Conditions
- male or female patients aged 18-25 years with moderate to severe acne vulgarisacne, isotretinoin, fish oil, mucocutaneous side effects
- Registration Number
- TCTR20240810002
- Lead Sponsor
- Ratchadapiseksompotch Fund Chulalongkorn university
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
1. male or female, aged 18-25 years, diagnosed with moderate to severe acne vulgaris 2. BMI < 29.9 3. ability to follow research protocols
Exclusion Criteria
1. Individuals with a history of used topical treatment for acne vulgaris within a past month 2. Those who have documented allergy to isotretinoin 3. individuals with a history of taking fish oil supplements within the past 3 months 4. Those who have undergone procedures or treatments for acne with any options 5. individuals with diseases associated with acne, such as PCOS 6. on current medication that impacts acne, such as corticosteroids, JAK inhibitors 7. individuals with dyslipidemia, liver disease 8. bleeding tendency 9. pregnant or breastfeeding women.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method impact of fish oil on efficacy of isotretinoin in acne improvement. baseline, 1 month, 2 months, 3 months the outcome was based on the investigator global assessment (IGA) score and the lesion counts (both inflammatory and non-inflammatory) on the entire face.
- Secondary Outcome Measures
Name Time Method