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A clinical trial to study the effects of two drugs, nalbuphine and fentanyl in patients undergoing caesarean section.

Phase 4
Recruiting
Conditions
Term Pregnant females undergoing caesarean section
Registration Number
CTRI/2017/08/009399
Brief Summary

To prolong the duration of  postoperative analgesia in caesarean section by adding adjuvants to bupivacaine in spinal blockade

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Female
Target Recruitment
150
Inclusion Criteria

Term Pregnant females with ASA Grade I,II.

Exclusion Criteria

1.Patient’s refusal 2.Any spine abnormality 3.Altered coagulation profile 4.Allergy to local anaesthetic 5.Recent myocardial infarction 6.Significant aortic stenosis Patients with neurological disorders Cardiac or respiratory system failure Any major hepatic or renal problem.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Sensory blockadeSensory blockade: continuously​ till onset then every 10 minutes​ till regression | Motor blockade at 5,10,15 minutes then every 10minutes till regression | 3.VAS: every 15 minutes in the first hour then hourly for 4 hours then at 12hours and 24 hours after spinal blockade
Motor blockadeSensory blockade: continuously​ till onset then every 10 minutes​ till regression | Motor blockade at 5,10,15 minutes then every 10minutes till regression | 3.VAS: every 15 minutes in the first hour then hourly for 4 hours then at 12hours and 24 hours after spinal blockade
VASSensory blockade: continuously​ till onset then every 10 minutes​ till regression | Motor blockade at 5,10,15 minutes then every 10minutes till regression | 3.VAS: every 15 minutes in the first hour then hourly for 4 hours then at 12hours and 24 hours after spinal blockade
Secondary Outcome Measures
NameTimeMethod
Sedation scaleComplications

Trial Locations

Locations (1)

Government Medical college patiala

🇮🇳

Patiala, PUNJAB, India

Government Medical college patiala
🇮🇳Patiala, PUNJAB, India
Dr Garima Jindal
Principal investigator
9646486062
garimajindal90@gmail.com

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