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Clinical Trials/CTRI/2018/08/015456
CTRI/2018/08/015456
Not yet recruiting
未知

Effect of fluid restriction and active fluid removal versus conventional fluid therapy on morbidity in ventilated pediatric patients:an open label randomized controlled trial

Dr Kaushik Maulik0 sites0 target enrollmentTBD

Overview

Phase
未知
Intervention
Not specified
Conditions
Health Condition 1: I958- Other hypotension
Sponsor
Dr Kaushik Maulik
Status
Not yet recruiting
Last Updated
4 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
4 years ago
Study Type
Interventional

Investigators

Sponsor
Dr Kaushik Maulik

Eligibility Criteria

Inclusion Criteria

  • 1\. All ventilated children between 2 completed months and 7 completed years admitted to PICU will be included
  • 2\. The included children must have received at least one fluid bolus
  • 3\. Must have achieved hemodynamic stability at enrolment defined by:
  • MAP \>5th centile
  • CRT \<2 seconds
  • Not required any more fluid bolus or inotropes in last 12 hours

Exclusion Criteria

  • 1\. Child with severe acute malnutrition (SAM)
  • 2\. Child with decompensated chronic liver disease and chronic kidney disease on RRT
  • 3\. Child with clinically suspected cardiogenic shock/myocarditis/acquired and congenital heart diseases in CCF
  • 4\. Children undergoing treatment for raised ICP with fluid restriction
  • 5\. Children with no evidence of fluid overload as assessed by body weight(defined as 10% increase from admission weight)
  • 6\. Children with severe anemia and hypoalbuminemia

Outcomes

Primary Outcomes

Not specified

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