Using Renal Elastography Measurements for Evaluation of Glomerulonephritis Patients

Not Applicable

Not yet recruiting

• Conditions: Evaluation of Biopcy Proven Glomerulonephritis Patients by Renal Shear Wave Elastography
• Interventions: Diagnostic Test: renal shear wave elastography

• Registration Number: NCT06623877
• Lead Sponsor: Assiut University

Brief Summary

All participants will clinically evaluated by history taking, full physical examination including body weight and assessment of fluid status, and blood and urine samples for lab analysis (serum creatinine, urea, sodium, potassium, corrected calcium, phosphorous, estimated glomerular filtration rate(GFR) by Cokcroft equation ((140 - age ) x body weight by Kg/creatinine by µmol )complete urine analysis including microscopic examination of urine , 24 hours urinary protein , haemoglobin level .

All participants will undergo renal shear wave elastography measurements. Values will be obtained from the upper, middle, and lower zones of each kidney. A total of six shear wave elastography measurements will be collected to get mean elastography values (MEVs) of each participant.

Detailed Description

We will collect results of MEV plus blood and urine samples of each participant then data will undergo statistical analysis to compare between MEV of healthy persons and biopcy proven glomerulonephritis patients

Study Timeline

• Status Verified: 2024-09
• Study First Submitted: 2024-09-24
• Study Start: 2024-10-01
• Study First Submitted QC: 2024-10-01
• Last Update Submitted: 2024-10-01
• Study First Posted: 2024-10-02
• Last Update Posted: 2024-10-02
• Primary Completion: 2025-10-01
• Study Completion: 2025-11-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group A: biopcy proven glomerulonephritis patients not started specific treatement	renal shear wave elastography	agroup of Biopcy proven glomerulonephritis patients not started specific treatement will undergo for renal shear wave elastography
Group B : healthy persons	renal shear wave elastography	A group of healthy persons will undergo for renal shear wave elastography

Primary Outcome Measures

Name	Time	Method
comparisons between the shear wave elastography measurements in GN patients and healthy persons .	One year

Trial Locations

Locations (1)

Faculty of medicine,Assiut universty,Egypy; 🇪🇬 Assiut, Egypt