Denture Stomatitis: cetylpyridinium chloride treatment with control group
Not Applicable
Active, not recruiting
- Conditions
- Denture StomatitisOral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon
- Registration Number
- ACTRN12609000460202
- Lead Sponsor
- Sao Paulo University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Active, not recruiting
- Sex
- All
- Target Recruitment
- 32
Inclusion Criteria
Removable dental prosrthesis wearers
Proper diagnosis of denture stomatitis
Exclusion Criteria
No history of antifungal use in the last 6 months
Negative medical history for radiotherapy, chemotherapy or immunodeficiency
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical improvement, measured according to the clinical parameters initially stablished - intensity and extent of mucosal erythema. Erythema intensity will be classified according to a coloured scale of eight grades varying from pale pink to bloody red. Extension of erythema will be objectively measured in square centimeters with the aid of digitized pictures and categorized in four classes: up to 25%; between 25 and 50%; between 50 and 75% and above 75% of the palate mucosa involved.[starting date, day 21, day 35]
- Secondary Outcome Measures
Name Time Method Colony forming units will be counted in Petri dishes with appropriate medium for growing Candida species. Sample collection will be performed with cytobrushes from palate mucosa and the prosthesis basis. These samples will be progressive diluted and dispensed in drops on the Petri dishes. Dishes will be incubated at 37oC to be read in 24, 48 and 72 hours.[starting date, day 21, day 35]