Pharmacokinetic study to assess the bioavailability of the cocoa flavanols catechin and epicatechin from different matrices.
Completed
- Conditions
- Cocoa and chocolate products have generated significant interest due to their association with various health-protective and therapeutic activities. Cocoa and chocolate are rich sources of flavan-3-ols, which are present in monomeric and polymeric forms.
- Registration Number
- NL-OMON22741
- Lead Sponsor
- ProDigest BVBATechnologiepark 3, 9052 Zwijnaarde, BelgiëTel: +32/ 9 264 59 78
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 6
Inclusion Criteria
1. Adults between 20 and 45 years old;
2. Non-smoking individuals;
Exclusion Criteria
1. Clinically significant abnormal liver biochemistry;
2. Clinically significant abnormal serum creatinin;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Area under the blood concentration - time curve (AUC).
- Secondary Outcome Measures
Name Time Method Maximal blood concentration (Cmax) and time to maximal blood concentration (Tmax).