Effect of a preoperative calorie restriction on renal function after cardiac surgery in patients at risk - CR_KCH

niversität zu Köln0 个研究点目标入组 82 人开始时间: 2011年11月23日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•1.men and women over 18 years
•2.caucasian origin
•3.scheduled cardiothoracic operation with employment of cardio-pulmonary bypass and a lead time of 11 days minimum.
•4.indication for cardiac surgery is determined by the cardiothoracic specialist
•5.Patient and/or legal guardian must be willing and able to give written informed consent
•6.chronic renal impairment with serum creatinine > 1,5 mg/dl or creatinine > 1,1 mg/dl with at least one of the following risk factors:
•a. Diabetes mellitus b. pAOD c. heart failure (EF < 50%)

•1.End-stage renal disease (patient on dialysis)
•2.Indwelling kidney transplant
•3.Malnutrition (BMI < 18,5 kg/m2)
•4.Body weight< 46 kg in male
•< 51 kg in female
•5.BMI > 35 kg/m2 or body weight > 120 kg
•6.catabolic state (serum albumine < 25 g/l)
•7.diet within the previous 4 weeks
•8.Inappetence
•9.Weight loss > 1 kg within the previous 2 weeks, if not explained by use of diuretics
•10.Hospital stay during the last 7 days prior to cardiac surgery
•11.Consuming underlying disease
•12.Uncontrolled local or systemic infection
•13.Contraindication for enteral nutrition.
•14.Known allergy against or incompatibility with ingredients of the employed formula-diet
•15.Pregnancy or breast feeding
•16.Participation in other interventional clinical trials.
•17.Missing safe method of contraception or missing occurence of menopause (in female)
•18.Professional or private relationship between subject and the investigators or dependence on the investigators.
•19.Placement in an institution based on official orders.

发起方

niversität zu Köln