Allergy Towards Grass and Bronchial Inflammation - Related to Immunotherapy and Exhaled Nitrogen Oxide

Not Applicable

• Conditions: Asthma, Bronchial; Allergic Rhinitis; Hypersensitivity, Immediate

• Registration Number: NCT00312312
• Lead Sponsor: Bispebjerg Hospital

Brief Summary

The purpose of this study is to evaluate the immunomodulatory effect of treatment of allergic rhinitis symptoms with specific immunotherapy by measurement of pulmonary inflammatory markers, and among others, exhaled nitric oxide.

Detailed Description

Not available

Study Timeline

• Study Start: 2006-03
• Study First Submitted: 2006-04-05
• Study First Submitted QC: 2006-04-05
• Study First Posted: 2006-04-10
• Status Verified: 2006-09
• Last Update Submitted: 2007-06-11
• Last Update Posted: 2007-06-12
• Study Completion: 2008-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Age 18-45 years old
• Skin prick test or RAS test and physical examination conclude that the patient will have a beneficial effect from specific immunotherapy

Exclusion Criteria

• Other diseases except atopic disease
• Pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Immunoglobulin E (IgE) status
Sputum examination
Condensation of exhaled air
Skin prick test
Spirometry
Methacholine provocation of the pulmonary system
Exhaled nitric oxide

Secondary Outcome Measures

Name	Time	Method
Questionnaire

Trial Locations

Locations (1)

Bispebjerg Hospital; 🇩🇰 Copenhagen, Denmark