NCT01875575已完成不适用
Oral Glucose in Normal-weight and Obese Volunteers
University Hospital, Basel, Switzerland2 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2013年2月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 24
- 试验地点
- 2
- 主要终点
- Effect of different oral glucose loads on secretion of satiation hormones
研究概览
简要总结
The objective of this study is to examine gastric emptying and satiety hormones after oral glucose stimulation in 2 different concentrations in normal-weight and obese patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 40 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy normal weight subjects with a body-mass index of 19.0-24.5 or healthy obese subjects with a body-mass index of > 30
- •Normal eating habits
- •Age 18-40 years
- •Stable body weight for at least three months
排除标准
- •Substance abuse
- •Regular intake of medications (except for oral contraceptives)
- •Medical or psychiatric illness
- •Any abnormality detected during the screening procedure
- •history of gastrointestinal disorders
- •food allergies
结局指标
主要结局
Effect of different oral glucose loads on secretion of satiation hormones
时间窗: 240min.
Plasma concentrations of glucose, insulin, glucagon, ghrelin, GLP-1, PYY and CCK are measured
次要结局
- Effect of different oral glucose loads on gastric emptying(240min.)
研究者
研究点 (2)
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