Evaluation of curcumin _ ginger mouth wash effect on salivary IL-1B levels in chronic periodontitis

Phase 3

• Conditions: generalized chronic periodontitis.; Chronic periodontitis, generalized; K05.32

• Registration Number: IRCT20180516039682N2
• Lead Sponsor: Zanjan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 14 January 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

patients older than 30 years
Patients with chronic moderate to severe periodontitis and probing depth > 4mm
Patients with at least 20 teeth in the mouth

Exclusion Criteria

History of Systemic Disease
Pregnant or lactating women
History of antibiotic prophylaxis 6 months prior to study or use of antibiotics in the last 3 months
Patients with mouth breathing
Patients with orthodontic appliances or dental prosthodontics
Patients with harmful habits such as smoking
People allergic to turmeric or ginger

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
evel of salivary IL-1b. Timepoint: Measurement of salivary IL-1b at the beginning of the study (before the intervention) and 14 days after the start of mouthwash use. Method of measurement: human IL-1b ELISA.