Comparing the effect of mouthwash containing curcumin and oral nanocurcumin on gingivitis in patients with chronic gingivitis

Phase 2

Recruiting

• Conditions: Gingivitis.; Gingivitis and periodontal diseases

• Registration Number: IRCT20220420054592N2
• Lead Sponsor: Yazd University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 6 March 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Patients with chronic gingivitis referred to the periodontics department of dental school
No systemic disease (no history of gallstones or gallstone obstruction, no active gastrointestinal diseases, liver disease or immunosuppressive system)
Age group 25 to 65 years old By matching age and gender in each group
Insensitivity to turmeric and its compounds based on patient's self-declaration
Needless to antibiotic prophylaxis
Non-smoking
Not using anti-inflammatory drugs for six weeks prior to and at the time of the check-up
Lack of attachment loss
Lack of periodontal treatment in the past six months
Lack of pregnancy or breastfeeding
No simultaneous anticoagulant and antiplatelet use

Exclusion Criteria

Lack of patient cooperation
Having symptoms of curcumin allergy

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Gingival Index. Timepoint: In the first session and two weeks after the start of using oral rinses or nanocurcumin capsules depending on the patient group. Method of measurement: A probe and principles of the gingival index system identified by Leo.;Plaque Index. Timepoint: In the first session and two weeks after the start of using oral rinses or nanocurcumin capsules depending on the patient group. Method of measurement: Plaque Index (silness-loe).;Papillary Bleeding Index. Timepoint: In the first session and two weeks after the start of using oral rinses or nanocurcumin capsules depending on the patient group. Method of measurement: A probe and record bleeding points around each tooth.