JPRN-UMIN000024330
Unknown
Phase 2
A phase II study of combination chemotherapy of oral tegafur/uracil, leucovorin and bevacizumab for patients not appropriate for intensive therapy with unresectable or recurrent colorectal cancer - A phase II study of UFT/LV and bevacizumab treatment
Dept of Surgical Oncology Osaka City University Graduate School of Medicine0 sites35 target enrollmentOctober 7, 2016
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- unresectable metastatic/recurrent colorectal cancer
- Sponsor
- Dept of Surgical Oncology Osaka City University Graduate School of Medicine
- Enrollment
- 35
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1\)Patients with a past history of severe drug allergy 2\)no other co\-existing malignancy or malignancy within the last five years prior to enrollment other than non\-melanoma skin cancer or in situ carcinoma of the cervix 3\)patients were pregnant or lactating 4\)Patients with psychiatric illness 5\)Patients with severe co\-morbidities (renal failure, liver dysfunction, uncontrolable diabetes mellitus and hypertension, heart failure) 6\)Patients with massive ascites or hydrothorax 7\)Patients with a symptomatic brain metastasis 8\)Patients with abdominal surgery within 28days 9\)Patients with perforated disease 10\)Patients with thrombosis 11\)Patiens with 3\+ proteinurea
Outcomes
Primary Outcomes
Not specified
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