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Incentive Spirometer Training in Type 2 Diabetes With Sarcopenia

Not Applicable
Not yet recruiting
Conditions
Sarcopenia
Type 2 Diabetes
Interventions
Behavioral: incentive spirometry
Registration Number
NCT06500221
Lead Sponsor
Yu-Shan Hsieh
Brief Summary

In patients with Type 2 diabetes, the risk of developing sarcopenia is three times higher compared to individuals with normal blood sugar levels. Sarcopenia is often accompanied by reduced physical activity, immobility, slow gait, and poor endurance. More importantly, previous studies have shown that sarcopenia leads to a decrease in mobility, which in turn results in reduced cardiopulmonary function, difficulty in breathing, and subsequently even less activity. In diabetic patients, this can cause poor control of blood sugar and lipids, as well as sarcopenic obesity, creating a vicious cycle. Therefore, preventing such a cycle is a crucial issue that needs attention. The incentive spirometer is widely used in physical, speech, and respiratory therapy, as well as in preventing postoperative pulmonary infections and improving sputum clearance. Consequently, this study aims to further confirm the role and effectiveness of incentive spirometry in improving lung function, activity endurance, and long-term blood sugar and lipid indices in patients with Type 2 diabetes combined with sarcopenia.

Detailed Description

In patients with Type 2 diabetes, the risk of developing sarcopenia is three times higher compared to individuals with normal blood sugar levels. Sarcopenia is often accompanied by reduced physical activity, immobility, slow gait, and poor endurance. More importantly, previous studies have shown that sarcopenia leads to a decrease in mobility, which in turn results in reduced cardiopulmonary function, difficulty in breathing, and subsequently even less activity. In diabetic patients, this can cause poor control of blood sugar and lipids, as well as sarcopenic obesity, creating a vicious cycle. Therefore, preventing such a cycle is a crucial issue that needs attention. The incentive spirometer is widely used in physical, speech, and respiratory therapy, as well as in preventing postoperative pulmonary infections and improving sputum clearance. Consequently, this study aims to further confirm the role and effectiveness of incentive spirometry in improving lung function, activity endurance, and long-term blood sugar and lipid indices in patients with Type 2 diabetes combined with sarcopenia.

The inclusion criteria:

1. Diagnosed with Type 2 diabetes (ICD-10 diagnosis codes: E10.x or E11.x)

2. Screened with a score of 4 or above on the screening self-administered sarcopenia (SARC-F) questionnaire.

3. Aged between 20-90 years old and able to communicate in Mandarin or Taiwanese

The exclusion criteria:

1. Patients with a functional status grade of ≥5 on the Modified Rankin Scale (MRS), indicating severe disability or bedridden condition.

2. Patients suffering from dementia, such as Alzheimer's disease, Parkinson's disease, etc.

3. Patients with acute psychiatric symptoms unable to communicate.

4. Currently diagnosed with chronic obstructive pulmonary disease (COPD) or any other respiratory system diseases.

5. Moderate or severe heart disease (New York Heart Association functional classification Class III or IV).

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
All
Target Recruitment
45
Inclusion Criteria
  • Diagnosed with Type 2 diabetes (ICD-10 diagnosis codes: E10.x or E11.x)
  • Screened with a score of 4 or above on the SARC-F questionnaire.
  • Aged between 20-90 years old and able to communicate in Mandarin or Taiwanese
Exclusion Criteria
  • Patients with a functional status grade of ≥5 on the Modified Rankin Scale (MRS), indicating severe disability or bedridden condition.
  • Patients suffering from dementia, such as Alzheimer's disease, Parkinson's disease, etc.
  • Patients with acute psychiatric symptoms unable to communicate.
  • Currently diagnosed with chronic obstructive pulmonary disease (COPD) or any other respiratory system diseases.
  • Moderate or severe heart disease (New York Heart Association functional classification Class III or IV).

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Type 2 diabetes combined with sarcopeniaincentive spirometryincentive spirometry intervention
Primary Outcome Measures
NameTimeMethod
Lung function:FEV13 months

Forced Expiratory Volume in the First Second (FEV1)

Lung function: FEV1/FVC ratio3 months

FEV1/FVC ratio

Lung function: FVC3 months

Forced Vital Capacity (FVC)

Secondary Outcome Measures
NameTimeMethod
Long-term Metabolic Indicators: TG3 months

Serum Triglycerides (TG)

Long-term Metabolic Indicators: HbA1c3 months

Glycated Hemoglobin (HbA1c)

Long-term Metabolic Indicators: TC3 months

Serum Total Cholesterol (TC)

Long-term Metabolic Indicators: HDL3 months

Serum High-Density Lipoprotein (HDL)

Long-term Metabolic Indicators: LDL3 months

Serum Low-Density Lipoprotein (LDL)

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