BLUC Study (BLUC Study)

Recruiting

• Conditions: Upper urothelial carcinoma (renal pelvis and ureter)

• Registration Number: jRCTs041250025

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2025-05-19
• Last Update Posted: 2025-06-10

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 280

Inclusion Criteria

1. Disease name Upper urothelial carcinoma (cancer of the renal pelvis and ureter) Stage 0a-3 (cTa-T3), cN0, cM0
2. Age. 18 to 80 years old
3. Performance Status (ECOG). 0 to 1
4. Patients with written consent to participate in the study

Exclusion Criteria

1. Those who have a history of treatment for bladder cancer prior to radical nephrectomy for UTUC
2. Those who have a history of treatment for UTUC in the past
3. Those who have metastatic lesions (lymph nodes, other organs, etc.) at the time of diagnosis
4. Those who have a history of radiation therapy
5. Those who are pregnant or may be pregnant, or are breastfeeding
6. Those who are judged by the principal investigator or sub-investigator to be unsuitable as research subjects

Study & Design

• Study Type: Interventional
• Study Design: parallel assignment

Primary Outcome Measures

Name	Time	Method
duration of recurrence-free period in the bladder	108-week observation period from the date of surgery	The period from the date of surgery to the date of confirmation of recurrence by cystoscopy. In cases with no follow-up, the period is terminated on the last day of confirmed recurrence-free period before the loss of follow-up.; However, for cases without 108-week follow-up, data on the presence or absence of recurrence at the last observation will be used. Deaths without intracisternal recurrence within 108 weeks shall be treated as no intracisternal recurrence.