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Clinical Trials/NCT01310920
NCT01310920UnknownNot Applicable

The Role of Angiotensinogen Gene Polymorphism in the Pathogenesis of Non-familial Sick Sinus Syndrome

China Medical University Hospital1 site in 1 country400 target enrollmentStarted: February 2011Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Enrollment
400
Locations
1

Study Overview

Brief Summary

Evidence has been documented for the close relationship between the arrhythmia pathogenesis and the gene expression in renin-angiotensin system. However, it remains unclear for involvement of RAS in the pathogenesis of non-familial sick sinus syndrome. The researchers thus investigated the possible relationship between non-familial sick sinus syndrome and the polymorphism and haplotype of the AGT promoter.

Study Design

Study Type
Observational
Observational Model
Case Control

Eligibility Criteria

Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • sick sinus syndrome

Exclusion Criteria

  • 1.Severe systemic disease.
  • 2.Acute coronary syndrome.
  • 3.bradycardia with reversible cause.

Investigators

Sponsor Class
Other

Study Sites (1)

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