NCT01310920UnknownNot Applicable
The Role of Angiotensinogen Gene Polymorphism in the Pathogenesis of Non-familial Sick Sinus Syndrome
China Medical University Hospital1 site in 1 country400 target enrollmentStarted: February 2011Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Enrollment
- 400
- Locations
- 1
Study Overview
Brief Summary
Evidence has been documented for the close relationship between the arrhythmia pathogenesis and the gene expression in renin-angiotensin system. However, it remains unclear for involvement of RAS in the pathogenesis of non-familial sick sinus syndrome. The researchers thus investigated the possible relationship between non-familial sick sinus syndrome and the polymorphism and haplotype of the AGT promoter.
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
Eligibility Criteria
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •sick sinus syndrome
Exclusion Criteria
- •1.Severe systemic disease.
- •2.Acute coronary syndrome.
- •3.bradycardia with reversible cause.
Investigators
Study Sites (1)
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