Prospective Cohort Study of Polycystic Kidney Disease in Thai Patients
- Conditions
- Polycystic kidney diseasesChronic kidney diseaseTotal kidney volumeADPKDGenetic study
- Registration Number
- TCTR20210324006
- Lead Sponsor
- Jongkolneenithi Foundation
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
Diagnosed of genetic polycystic kidney diseases (PKD) from either clinical criteria or genetic study
Exclusion Criteria
Existing non-genetic cause of PKD
eGFR of less than 6 ml/min/m2
Kidney transplant recipient
Received renal replacement therapy except for indication of acute kidney injury
Pregnancy
Terminally ill eg. advance-staged heart failure with NYHA class IV, advance-staged lung disease, cirrhosis CTP score B or C, PLUS Karnofsky Performance Score of 40 or less
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Rate of eGFR reduction 60 months after enrollement CKD-EPI equation
- Secondary Outcome Measures
Name Time Method Incidence of eGFR reduction of 40% or more At 60 months after enrollment CKD-EPI equation,All-cause mortality At 60 months after enrollment Frequency,End-stage renal disease At 60 months after enrollment Frequency,Major adverse cardiovascular events At 60 months after enrollment Frequency,Polycystic kidney disease-related complications At 60 months after enrollment Frequency,Interventions associated with polycystic kidney diseases At 60 months after enrollment Frequency