CARDIOBASE Bern PCI Registry
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 10,000
- 试验地点
- 1
- 主要终点
- Number of patients with death
研究概览
简要总结
The aim of the CARDIOBASE Bern PCI registry is to collect baseline clinical and procedural data as well as to assess the clinical outcomes of all patients undergoing percutaneous coronary intervention (PCI) at Bern University Hospital. All patients undergoing PCI with or without stent implantation will be prospectively registered. Device use is according to the decision of the treating physician and independent of this registry. At hospital discharge and one year, the following outcomes will be assessed: death, cardiac death, myocardial infarction, stent thrombosis, repeat revascularisation, stent thrombosis, stroke, bleeding, renal failure and vascular complications.
详细描述
Background
Percutaneous Coronary Intervention (PCI) is the most frequently medical intervention performed worldwide. Coronary heart disease (CAD) remains the leading cause of death, although advances in the management of acute myocardial infarction (MI) have reduced in-hospital mortality from 16% in the mid-1980s to around 4 to 6%. Several breakthroughs have accounted for improvement of cardiovascular outcomes, including the use and further improvement of coronary stents and antiplatelet therapy. Regarding stents, bare metal stents were first introduced but associated with a high risk of restenosis, something which was successfully addressed by the introduction of drug-eluting stents.
All benefits and shortcomings of newly introduced devices and drug therapies are evaluated in large randomized controlled trials (RCT). Registries provide useful insights into novel associations that cannot be addressed by RCT.
The aim of the CARDIOBASE Bern PCI registry is to collect baseline clinical and procedural data as well as to assess the clinical outcomes of all patients undergoing percutaneous coronary intervention at Bern University Hospital. All patients undergoing PCI with or without stent implantation will be prospectively registered. Device use is according to the decision of the treating physician and independent of this registry.
Objective
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient above 18 years of age
- •Undergoing PCI at Bern University Hospital
- •Written informed consent
- •Exclusion Criteria
- •No informed consent
排除标准
- 未提供
结局指标
主要结局
Number of patients with death
时间窗: At discharge, expected to be on average after 2 days, & at one year
次要结局
- Number of patients with myocardial infarction(At discharge, expected to be on average after 2 days, & at one year)
- Number of patients with stent thrombosis(At discharge, expected to be on average after 2 days, & at one year)
- Number of patients with stroke(At discharge, expected to be on average after 2 days, & at one year)
- Number of patients with(At discharge, expected to be on average after 2 days, & at one year)
- Number of patients with repeat revascularisation(At discharge, expected to be on average after 2 days, & at one year)
- Number of patients with bleeding(At discharge, expected to be on average after 2 days, & at one year)