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Clinical Trials/NCT05262933
NCT05262933
Completed
Not Applicable

Effect of Preoperative Coffee Consumption on Intraoperative and Post Operative Outcomes in Cesarean Section With Spinal Anesthesia

TC Erciyes University1 site in 1 country2 target enrollmentStarted: March 15, 2022Last updated:

Overview

Phase
Not Applicable
Status
Completed
Enrollment
2
Locations
1
Primary Endpoint
hypotension

Overview

Brief Summary

The prospective study is planned in a university hospital. Spinal anesthesia is widely used for cesarean section currently for its safety, low cost, reliability, easiness to administer, immediate effect, and well-operating conditions. However spinal anesthesia has some complications as hypotension, bradycardia and Post Dural Puncture Headache (PDPH). A practical strategy for avoiding hypotension during initiation of spinal anesthesia for cesarean delivery includes intravenous crystalloid, in conjunction with administration of vasopressors. PDPH is one of the most frequent complications of spinal anesthesia. Conservative therapies such as bed rest, hydration, and caffeine are commonly used as management. For this study, coffee group of patients will be given unsweetened brewed coffee 150 ml until 2-4 hours before surgery. Patients who accept to drink brewed coffee ( coffee group) and water( control group) will be included in the study. The patient's heart rate, blood pressure, oxygen saturation will be monitored and recorded during operation. Intraoperative will be recorded to amount of vasopressor and intraveous crystalloid. Whether the patient develops PDPH in the postoperative period will be followed for 3 days. In addition abdominal auscultation for bowel sounds hourly and the time of first bowel movements will be recorded. According to the patient's statement, the time of first flatulence and defecation will be followed and recorded.

Study Design

Study Type
Observational
Observational Model
Case Control
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to 45 Years (Adult)
Sex
Female
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • patients who accept to participate in the study
  • patient who limit the consumption of caffeinated beverages such as coffee and tea during pregnancy
  • Patients with known caffeine or coffee allergy

Exclusion Criteria

  • patients who refuse to participate in the study
  • Patients with known cardiovascular disease
  • Patients with known cerebrovascular disease
  • patients with known neurological, neurodegenerative or psychiatric disease
  • patients with known liver failure
  • patient followed up with eclampsia and preaclampsi
  • higher number of needle passes in spinal anesthesia
  • patients treated with an antiemetic

Outcomes

Primary Outcomes

hypotension

Time Frame: intraoperative time period

effects of orally coffee intake on spinal anesthesia induced hypotension

Secondary Outcomes

  • Post-dural puncture headache(post operative 3 days)
  • intestinal motility, first flatus(post operative 3 days)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Gamze Talih

Associate Professor

TC Erciyes University

Study Sites (1)

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