There is a Value of Luteinizing Hormone Predictive of in Vitro Fertilization Treatment Outcome in Antagonist Protocols?
Phase 4
Completed
- Conditions
- Female Infertility
- Interventions
- Other: LH value
- Registration Number
- NCT02328924
- Lead Sponsor
- U.O.S. Procreazione Medicalmente Assistita e Congelamento Gameti
- Brief Summary
This study, prospective randomized controlled trial, tried to identify a cut off value of luteinizing hormone predictive of in vitro fertilization outcome in a fixed or flexible gonadotropin-releasing hormone antagonist protocols.
202 norma-ovulatory women \< 39 years were randomized to fixed or flexible group in GnRH antagonist protocols The follicular phase profile of luteinizing hormone, estradiol and progesterone in the two study groups was measured. Total number of retrieved oocytes, implantation and pregnancy rate were recorded.
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- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 213
Inclusion Criteria
-
- age <39 years; (2) normal menstrual cycle (range of 26-32 days); (3) baseline follicle stimulating hormone levels < 12 IU/ml; (4) body mass index (BMI) between 18-30 Kg/m2; (5) no oral contraceptive pills taken in the last year
Exclusion Criteria
- polycystic ovaries, age >39 years
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description LH value in fixed group LH value LH value predictive of IVF in 104 patients entered in fixed protocol LH value in flexible group LH value LH value predictive of IVF in 109 patients entered in flexible protocols
- Primary Outcome Measures
Name Time Method number of mature oocytes recruited after IVF with antagonist protocol partecipant will be followed for the duration of the cycle of IVF and for the following three months
- Secondary Outcome Measures
Name Time Method