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Prevalence of hiv-associated neurocognitive disorders (HAND).

Withdrawn
Conditions
cerebral dysfunction
hiv-associated neurocognitive disorder
10002252
10009841
Registration Number
NL-OMON35476
Lead Sponsor
niversitair Medisch Centrum Utrecht
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Withdrawn
Sex
Not specified
Target Recruitment
225
Inclusion Criteria

- diagnosis hiv
- 18 years or older
- capable of speaking and reading Dutch
- adequate sight and hearing ability to join the study;Inclusion criteria controlgroup Diabetes mellitus:
- diagnosis DM 2
- 18 years or older
- capable of speaking and reading Dutch
- adequate sight and hearing ability to join the study
- GFR>30;Inclusion criteria controlgroup healthy volunteer:
- 18 years or older
- capable of speaking and reading Dutch
- adequate sight and hearing ability to join the study

Exclusion Criteria

- drugs- and/ or alcohol abuses (in the past two years)
- Diagnosis of depression (current or last year)
- current use of anti-depressive or anti-psychotic medication
- history of learning disabilities, dyslexia or mental retardation
- history of Cardiac Vascular Attack or neuro-syphilis with sustained brain damage
- Vascular diseases (cerebral, cardiac and peripheral)
- (pre)terminal kidney failure, defined as GFR <30
- Pregnancy;Exclusion criteria control group diabetes mellitus:
- drugs- and/ or alcohol abuses (in the past two years)
- Diagnosis of depression (current or last year)
- current use of anti-depressive or anti-psychotic medication
- history of learning disabilities, dyslexia or mental retardation
- history of Cardiac Vascular Attack or neuro-syphilis with sustained brain damage
- Vascular diseases (cerebral, cardiac and peripheral)
- (pre)terminal kidney failure, defined as GFR <30
- symptomatic hypoglycaemia in the past 3 days
- Pregnancy;Exclusion criteria control group of healthy volunteers:
- drugs- and/ or alcohol abuses (in the past two years)
- Diagnosis of depression (current or last year)
- current use of anti-depressive or anti-psychotic medication
- history of learning disabilities, dyslexia or mental retardation
- history of Cardiac Vascular Attack or neuro-syphilis with sustained brain damage
- Vascular diseases (cerebral, cardiac and peripheral)
- (pre)terminal kidney failure, defined as GFR <30
- Pregnancy

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Is the prevalence of a positive HAND screening test-outcome with the hiv<br /><br>dementia scale (less than 14 points is a positive outcome), higher in people<br /><br>living with hiv, compared to people living with diabetes mellitus tye 2 or<br /><br>healthy volunteers?</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Can we identify determinants associated with a positive result on the hiv<br /><br>dementia scale?</p><br>
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