Prevalence of hiv-associated neurocognitive disorders (HAND).
- Conditions
- cerebral dysfunctionhiv-associated neurocognitive disorder1000225210009841
- Registration Number
- NL-OMON35476
- Lead Sponsor
- niversitair Medisch Centrum Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Withdrawn
- Sex
- Not specified
- Target Recruitment
- 225
- diagnosis hiv
- 18 years or older
- capable of speaking and reading Dutch
- adequate sight and hearing ability to join the study;Inclusion criteria controlgroup Diabetes mellitus:
- diagnosis DM 2
- 18 years or older
- capable of speaking and reading Dutch
- adequate sight and hearing ability to join the study
- GFR>30;Inclusion criteria controlgroup healthy volunteer:
- 18 years or older
- capable of speaking and reading Dutch
- adequate sight and hearing ability to join the study
- drugs- and/ or alcohol abuses (in the past two years)
- Diagnosis of depression (current or last year)
- current use of anti-depressive or anti-psychotic medication
- history of learning disabilities, dyslexia or mental retardation
- history of Cardiac Vascular Attack or neuro-syphilis with sustained brain damage
- Vascular diseases (cerebral, cardiac and peripheral)
- (pre)terminal kidney failure, defined as GFR <30
- Pregnancy;Exclusion criteria control group diabetes mellitus:
- drugs- and/ or alcohol abuses (in the past two years)
- Diagnosis of depression (current or last year)
- current use of anti-depressive or anti-psychotic medication
- history of learning disabilities, dyslexia or mental retardation
- history of Cardiac Vascular Attack or neuro-syphilis with sustained brain damage
- Vascular diseases (cerebral, cardiac and peripheral)
- (pre)terminal kidney failure, defined as GFR <30
- symptomatic hypoglycaemia in the past 3 days
- Pregnancy;Exclusion criteria control group of healthy volunteers:
- drugs- and/ or alcohol abuses (in the past two years)
- Diagnosis of depression (current or last year)
- current use of anti-depressive or anti-psychotic medication
- history of learning disabilities, dyslexia or mental retardation
- history of Cardiac Vascular Attack or neuro-syphilis with sustained brain damage
- Vascular diseases (cerebral, cardiac and peripheral)
- (pre)terminal kidney failure, defined as GFR <30
- Pregnancy
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Is the prevalence of a positive HAND screening test-outcome with the hiv<br /><br>dementia scale (less than 14 points is a positive outcome), higher in people<br /><br>living with hiv, compared to people living with diabetes mellitus tye 2 or<br /><br>healthy volunteers?</p><br>
- Secondary Outcome Measures
Name Time Method <p>Can we identify determinants associated with a positive result on the hiv<br /><br>dementia scale?</p><br>