Endothelial Dysfunction Induced by Postprandial Lipemia

Phase 2

Completed

• Conditions: Healthy Subjects

• Registration Number: NCT00660491
• Lead Sponsor: Norwegian University of Science and Technology

Brief Summary

Postprandial lipemia and exercise oppose each other in terms of cardiovascular risk, however the mechanism of their interaction is not well understood.

Therefore we want to study vascular function, as assessed by brachial artery (BA) flow mediated dilation (FMD), in healthy men before and after a high fat meal (HFM) preceded (16-18 hrs) by rest, a single bout of continuous moderate intensity exercise (CME), and high intensity interval exercise (HIIE).

Detailed Description

Not available

Study Timeline

• Study Start: 2008-01
• Study First Submitted: 2008-04-15
• Study First Submitted QC: 2008-04-15
• Study First Posted: 2008-04-17
• Primary Completion: 2008-09
• Study Completion: 2008-10
• Status Verified: 2012-01
• Last Update Submitted: 2012-01-05
• Last Update Posted: 2012-01-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 8

Inclusion Criteria

• male, 20-40years, BMI between 25 and 30, resident in Trondheim.

Exclusion Criteria

• unstable angina, CHD, heart failure,

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Flow mediated dilatation	baseline, post exercise, 30min, 2hour, 4hour post exercise

Secondary Outcome Measures

Name	Time	Method
blood lipid profile	same as flow mediated dilatation

Trial Locations

Locations (1)

NTNU; 🇳🇴 Trondheim, Norway