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临床试验/CTRI/2025/01/079621
CTRI/2025/01/079621尚未招募不适用

Association between physical activity and sarcopenia among individuals with knee osteoarthritis: An observational study

Sri Ramachandra Institute of Higher Education and Research1 个研究点 分布在 1 个国家目标入组 84 人开始时间: 2025年2月10日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
84
试验地点
1
主要终点
Body Composition Analyser

研究概览

简要总结

BACKGROUND

As individuals age, several changes in body composition occur which include the progressive decline in muscle mass and strength, which begins as early as the 30s. An increase in Adiposity (accumulation of fat) tends to increase. These changes have significant implications for health and well-being. Increased adiposity is associated with knee osteoarthritis (KOA), which is a well-known risk factor for various health conditions, including cardiovascular diseases, diabetes, and reduced quality of life. Sarcopenia refers to the loss of skeletal muscle mass, strength, and physical performance. It contributes to frailty, disability, and decreased overall functioning. When sarcopenia and KOA coexist, this combination poses additional health risks and challenges.

AIM:

The aim of this study is to investigate the association between physical activity levels and the prevalence of sarcopenia in individuals diagnosed with knee osteoarthritis.

OBJECTIVE:

Primary objective:

â The primary objective of this study is to determine the impact of physical activity levels on the development of sarcopenia in individuals with knee osteoarthritis.

Secondary objectives: To assess the differences in physical activity levels and sarcopenia scores among individuals with knee osteoarthritis.

To explore the relationship between physical activity levels, sarcopenia, and knee osteoarthritis.

METHODOLOGY:

Study design: Observational Study

Study sampling: Purposive Sampling

Study duration: 3 months or  6 months

Study setting: Out-Patient Physiotherapy Department, Sri Ramachandra Hospitals Study population: Knee Osteoarthritis

Study blinding: Group allocator, Outcome assessor, Statistics analyzer.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • Subjects identified with knee pain and asymptomatics Age18 years including both men and women.

排除标准

  • Have other significant musculoskeletal or neurological conditions affecting mobility.
  • Subjects who are unable to participate in physical activity assessments or interventions Have a history of significant cardiovascular events or conditions that may limit exercise participation.
  • Are currently undergoing treatment that may affect muscle mass or physical performance.

结局指标

主要结局

Body Composition Analyser

时间窗: At the Baseline

次要结局

  • The International Physical Activity Questionnaire (IPAQ)(At baseline)

研究者

申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Moneka C

Sri Ramachandra Institute of Higher Education and Research

研究点 (1)

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