Close Contact Self-Testing Among Contacts of Individuals With COVID-19 Infection
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 3
- 试验地点
- 2
- 主要终点
- Number of Positive Contacts
研究概览
简要总结
Widespread testing and contact tracing are critical to controlling the COVID-19 epidemic. Distribution of COVID-19 self-test kits can augment public health contact tracing efforts, as individuals with COVID-19 can distribute self-testing to close contacts. This approach can increase case detection by facilitating testing among exposed individuals, and potentially ameliorate stigma, fear, and medical mistrust associated with COVID-19 among vulnerable populations.
The central hypothesis of this study is that distribution of SARS-CoV-2 self-tests to close contacts of among individuals with COVID-19 infection can increase case detection compared with a standard contact referral strategy.
详细描述
Strategies to increase testing among individuals exposed to COVID-19 are needed. One approach to increase testing and case detection is to distribute home test kits to close contacts of individuals with COVID-19. This approach decreases logistic barriers to testing, potential exposures to COVID-19, and reduces potential stigma and fear associated with facility-based COVID-19 testing.
The investigators will conduct a cohort study of individuals diagnosed with COVID-19 in the C-STRAND trial (NCT04797858), in order to determine if distribution of self-test kits to close contacts of of individuals with COVID-19 can increase case detection compared with a standard contact referral strategy among. Individuals diagnosed with COVID-19 who were randomized to the self-test (intervention) arm or received self-test kits will be assigned to receive additional self-test kits to distribute to close contacts. Individuals diagnosed with COVID-19 who were randomized to the test referral (control) arm or received test referrals will be assigned to receive text message referrals to give their close contacts to seek testing if needed. COVID-19 case detection and test uptake will be measured in both arms.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18 years of age or older
- •Has a working telephone number
- •Willing and able to provide informed consent
排除标准
- •Severe symptoms requiring immediate medical attention
- •Younger than 18 years of age
- •Does not have a working telephone number
- •Unable or unwilling to provide informed consent
结局指标
主要结局
Number of Positive Contacts
时间窗: 8 weeks
Number of close contacts who test positive for COVID-19
次要结局
- Number of Positive Contacts (End of Study)(Through study completion, up to one year)
- Number of Contacts Tested(8 weeks)
- Number of Contacts Tested (End of Study)(Through study completion, up to one year)
- Number of Household Contacts Tested(8 weeks)
- Number of Household Contacts Tested (End of Study)(Through study completion, up to one year)
研究者
Robert Gross
Professor of Medicine
University of Pennsylvania