Piloting Pathways With Lung Cancer Patients

Not Applicable

Completed

Conditions: Metastatic Lung Cancer

Interventions: Behavioral: Pathways

Registration Number: NCT04161157

Lead Sponsor: Laurie McLouth

Brief Summary: The purpose of this research is to determine the feasibility of a new supportive intervention, called Pathways, for patients with advanced stage and metastatic lung cancer.

Detailed Description: In this study, investigators will first test the Pathways procedures with 6 patients to identify any improvements that need to be made. Then, investigators will test the feasibility of the Pathways intervention with 20 patients who are undergoing cancer treatment for advanced stage or metastatic lung cancer. Pathways is designed to help patients set and pursue personal goals during lung cancer treatment. In this study, investigators want to see if they can recruit patients with lung cancer who are being treated at the University of Kentucky Markey Cancer Center to participate in the Pathways intervention.

Recruitment & Eligibility

Status: COMPLETED

Sex: All

Target Recruitment: 53

Inclusion Criteria

new or recurrent stage IIIB, stage IIIC or stage IV non-small cell lung cancer (NSCLC) or extensive stage SCLC
18 years of age or older
ECOG PS 0-2/Karnofsky 60-100
3 to 12 weeks into active cancer treatment

Exclusion Criteria

unstable brain metastases
cognitive or psychiatric condition for which participating would be inappropriate
unable to speak and read English

Study & Design

Study Type: INTERVENTIONAL

Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Pathways	Pathways	Pathways is designed to help patients identify and pursue values-based goals and address potential goal obstacles, including lung cancer stigma.

Primary Outcome Measures

Name	Time	Method
Feasibility of Enrollment: Percentage of Eligible and Approached Patients Who Agree to Participate	9 months	Percentage of eligible and approached patients who agree to participate
Acceptability: Ratings	9 months	Mean acceptability ratings on individual items of acceptability developed by study team (e.g., convenience of the intervention, helpfulness of the intervention, relevance of the intervention; scores of at least 7/10 on each item, possible range = 1-10, higher scores indicate higher acceptability).

Secondary Outcome Measures

Name	Time	Method
Hope - State Hope Scale (Snyder)	9 months	Brief measure of agency and pathways thinking. 6 items responded to on a scale of 1 = definitely false to 8 = definitely true. Items are summed for a total score (possible range = 6 - 48). Higher scores indicate higher hope.
Lung Cancer Stigma - Lung Cancer Stigma Inventory (Hamann)	9 months	measure of lung cancer stigma. 25 items making up three subscales (perceived stigma, internalized stigma, and constrained disclosure). Items are responded to on a scale of 1 = not at all to 5 = extremely. Items are summed, with a higher score indicating greater lung cancer stigma/worse outcome (possible total score range = 25-125) . Clinical cutoff of a total score of 37.5 is suggested in literature as significant levels of stigma.
Purpose - PROMIS Meaning and Purpose 4a	9 months	Brief measure assessing one's sense of purpose and that there are reasons for living; 4 items responded to on a scale of 1 = not at all to 5 = very much (possible raw score range = 4 - 20). Higher scores indicate greater meaning and purpose.
PROMIS Satisfaction With Participation in Social Roles - Short Form 8a	9 months	Brief measure of satisfaction with ability and participation in activities and roles (e.g., work at home, regular personal and household responsibilities, do things for family) Higher scores indicate more satisfaction with participation. Raw scores range from 8 to 40. 8 items are responded to on a scale of 1 = not at all to 5 = very much.
Distress - PROMIS Depression Short Form 6a	9 months	Brief measure assessing sense of worthlessness, helplessness, depression, etc. 6 items are responded to on a scale of 1 = never to 5 = always (possible raw scores range from 6-30). Higher scores indicate greater distress.