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Clinical Trials/CTRI/2025/04/085666
CTRI/2025/04/085666
Completed
Phase 2

A Randomized Controlled Trial (RCT) to assess the effect of nurse-led nutrition and exercise intervention on nutritional status, activities of daily living and quality of life among patients with gastro-intestinal cancer at IRCH, AIIMS, New Delhi.

Ms Akansha1 site in 1 country300 target enrollmentStarted: August 1, 2025Last updated:

Overview

Phase
Phase 2
Status
Completed
Sponsor
Ms Akansha
Enrollment
300
Locations
1
Primary Endpoint
nutritional status

Overview

Brief Summary

The thesis research protocol focuses on a randomized controlled trial (RCT) to assess the impact of a nurse-led nutrition and exercise intervention on the nutritional status, activities of daily living, and quality of life among patients with gastrointestinal cancer at IRCH, AIIMS New Delhi. The study aims to evaluate how such an intervention can improve patient outcomes compared to standard care. The primary objectives include assessing changes in nutritional status, activities of daily living, and quality of life, while the secondary objectives explore the relationships between demographic factors and outcomes, along with patient satisfaction. A total of 300 patients will participate, randomized into intervention and control groups, with the intervention group receiving structured dietary advice and supervised exercise plans for 8 weeks. Data collection will include tools like biophysiological assessments and validated questionnaires. The study aims to address gaps in low-resource settings, providing a model for cost-effective, sustainable care to enhance patient recovery and quality of life.

Study Design

Study Type
Interventional
Allocation
Coin toss, Lottery, toss of dice, shuffling cards etc
Masking
Investigator Blinded

Eligibility Criteria

Ages
18.00 Year(s) to 99.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Patients who are 18 years Able to understand English or Hindi language Diagnosed with Gastro intestinal cancer 1-2 cycle of Neo Adjuvant therapy Eastern Cooperative Oncology Group Performance Status Score from 1 to 4 Having at least one caregiver of age more than 18 years Patients who are physically and mentally stable.

Exclusion Criteria

  • Patients who were unwilling to participate will be excluded from the study Patients who cannot read and write Hindi & English language Patients with advanced cancer.

Outcomes

Primary Outcomes

nutritional status

Time Frame: at base line at 1 month at 2 month at 3 month

Secondary Outcomes

  • activities of daily living(at base line at 1 month at 2 month at 3 month)
  • quality of life(at base line at 1 month at 2 month at 3 month)

Investigators

Sponsor
Ms Akansha
Sponsor Class
Other [self]
Responsible Party
Principal Investigator
Principal Investigator

Ms Akansha

College of Nursing AIIMS New Delhi

Study Sites (1)

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