Short Term Outcome Following Post Operative Enhanced Recovery Implementation in Patients With Perforated Peptic Ulcer

Not Applicable

Completed

• Conditions: Emergent Surgery; Perforated Peptic Ulcer
• Interventions: Procedure: Post operative enhanced recovery elements

• Registration Number: NCT06570018
• Lead Sponsor: Assiut University

Brief Summary

This study aimed to evaluate the effect of implementing post operative enhanced recovery on perforated peptic ulcer surgery outcome.

The current study anticipated better outcomes in the form of early functional recovery, reduced length of hospital stays, less thirty days post operative morbidity, and better gastrointestinal quality of life after implementing post operative enhanced recovery in patients with perforated peptic ulcer.

Detailed Description

This study aimed to evaluate the effect of implementing post operative enhanced recovery on perforated peptic ulcer surgery outcomes.

Methods: Quasi- experimental research design was utilized. The study was conducted at Assiut University Hospital.

A purposive sample of thirty patients (study group) who received postoperative enhanced recovery after open surgical repair of perforated peptic ulcer compared with thirty patients (control group) who exposed to routine care.

patient assessment sheet and gastrointestinal quality of life index were the tools used for data collection.

Study Timeline

• Study Start: 2023-10-01
• Primary Completion: 2024-07-15
• Study Completion: 2024-08-15
• Study First Submitted: 2024-08-20
• Study First Submitted QC: 2024-08-22
• Study First Posted: 2024-08-26
• Status Verified: 2025-01
• Last Update Submitted: 2025-01-27
• Last Update Posted: 2025-01-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Age ranged from 18 to 65 years,
• Diagnosed with perforated peptic ulcer,
• Ulcer size less than 10 mm.
• Underwent emergent surgical intervention

Exclusion Criteria

• Malignant ulcer.
• Other GIT diseases (corn's disease & ulcerative colitis)
• Pregnant women
• Psychiatric or neurological illness.
• Who refused to participate in the study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Enhanced recovery group	Post operative enhanced recovery elements	who received postoperative enhanced recovery after open surgical repair for perforated peptic ulcer

Primary Outcome Measures

Name	Time	Method
Gastrointestinal functional recovery(first flatus passage)	Within the first 24 hours postoperative or more	Tool; Patient assessment sheet; * It was developed by researchers based on literatures review to assess postoperative clinical data (part 2) as gastrointestinal functional recovery (first flatus passage) through physical examination.; the mean score of time for two groups was compared
Gastrointestinal functional recovery (first bowel movement)	Within the first 24 hours postoperative or more	Tool; Patient assessment sheet; * It was developed by researchers based on literatures review to assess postoperative clinical data (part 2) as gastrointestinal functional recovery (first bowel movement) through physical examination.; * The mean score of time for two groups was compared
Legnth of hospital stay	seven days up to two weeks	Hospitalization duration from admission up to discharge Mean score of days for two groups will be compared.
Gastrointestinal functional recovery(first stool passage)	First stool passage within three days postoperative or more	Tool; Patient assessment sheet; - It was developed by researchers based on literatures review to assess postoperative clinical data (part 2) as gastrointestinal functional recovery (first stool passage) postoperative.through health history.; The mean score of time for two groups was compared
postoperative complications	Immediately post operative up to thirty days postoperative	post operative complications included complications that occured within 30- days post operative. Every patient had been assessed for developing pneumonia, admission to critical care, abdominal collection, intra-abdominal abscess, suture leakage, omental patch leakage, septic shock, prolonged ileus, surgical site infection, urinary tract infection, deep venous thrombosis (DVT), and reoperation

Secondary Outcome Measures

Name	Time	Method
gastrointestinal quality of life	Before hospital dicharge and after thirty days postoperative	gastrointestinal quality of life was evaluated for all patients before discharge and after thirty days postoperative using Gastrointestinal quality of life index (Eypasch, 1993).; It is a 36-item scale divided into five domains; GIT symptoms (10 items), physical (6 items), emotion (6 items), social (2 items) and disease specific (8 items) Cronbach's alpha was 0.89; Scoring: Each item is based on a 0-4 Likert scale with 0 being least desirable to 4 being the most desirable option. The total scores represent Gastrointestinal Quality of Life Index. It ranges from 0 to 144 with higher scores indicating a better quality of life

Trial Locations

Locations (1)

Faculty of Nursing; 🇪🇬 Assiut, Egypt