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Clinical Trials/CTRI/2023/07/055039
CTRI/2023/07/055039
Not yet recruiting
未知

Clinical and Radiological evaluation of periodontal intrabony defects using 1% Melatonin gel with Demineralized freeze-Dried Bone Allograft (DFDBA) and its effect on Receptor Activator of Nuclear factor Kappa-B Ligand (RANKL) and Osteoprotegerin (OPG) levels in Gingival Crevicular Fluid - A Randomized Controlled Trial - NI

G Laxmi Kavya0 sites0 target enrollmentTBD

Overview

Phase
未知
Intervention
Not specified
Conditions
Not specified
Sponsor
G Laxmi Kavya
Status
Not yet recruiting
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Interventional

Investigators

Sponsor
G Laxmi Kavya

Eligibility Criteria

Inclusion Criteria

  • 1\.Patients with localized or generalized periodontitis of stage\-II and stage\-III with grade B and C as per 2017 classification
  • 2\.Two and three walled intrabony defects with radiologic vertical bone loss of \>\= 3mm at baseline and a PPD \>\=5mm when persistent after non\-surgical therapy

Exclusion Criteria

  • 1\.Patients with poor oral hygiene
  • 2\.Uncontrolled systemic diseases
  • 3\.Patients under antibiotic therapy
  • 4\.Smokers, tobacco chewers
  • 5\.Pregnant and lactating women
  • 6\.Patients receiving periodontal treatment during last 6 months
  • 7\.Patients under melatonin supplement therapies

Outcomes

Primary Outcomes

Not specified

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