CTRI/2023/07/055039
Not yet recruiting
未知
Clinical and Radiological evaluation of periodontal intrabony defects using 1% Melatonin gel with Demineralized freeze-Dried Bone Allograft (DFDBA) and its effect on Receptor Activator of Nuclear factor Kappa-B Ligand (RANKL) and Osteoprotegerin (OPG) levels in Gingival Crevicular Fluid - A Randomized Controlled Trial - NI
G Laxmi Kavya0 sites0 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- G Laxmi Kavya
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\.Patients with localized or generalized periodontitis of stage\-II and stage\-III with grade B and C as per 2017 classification
- •2\.Two and three walled intrabony defects with radiologic vertical bone loss of \>\= 3mm at baseline and a PPD \>\=5mm when persistent after non\-surgical therapy
Exclusion Criteria
- •1\.Patients with poor oral hygiene
- •2\.Uncontrolled systemic diseases
- •3\.Patients under antibiotic therapy
- •4\.Smokers, tobacco chewers
- •5\.Pregnant and lactating women
- •6\.Patients receiving periodontal treatment during last 6 months
- •7\.Patients under melatonin supplement therapies
Outcomes
Primary Outcomes
Not specified
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