Short- and long-term effects of low-level and high-intensity laser therapy as an adjunct to rehabilitation exercise on clinical outcomes among adults with mild to moderate knee osteoarthritis: a randomized control trial

BTL Industries Malaysia Sdn Bhd0 个研究点目标入组 60 人开始时间: 2021年12月10日最近更新: 2022年11月21日

适应症

试验速览

暂无简介。

•The inclusion criteria will be: (1) adults of both genders aged 18 to 75 years, (2) diagnosed with symptomatic (pain and/or stiffness) unilateral or bilateral knee osteoarthritis based on the American College of Rheumatology criteria (Nazari et al., 2019), (3) persistent knee pain with intensity at least 3 on a 10-cm visual analog scale (VAS) for more than 3 months during activities such as going up-and downstairs, sitting or squatting (Alayat et al., 2017, Nazari et al., 2019), (4) degenerative osteoarthritic knee of grade 2 (mild) to 3 (moderate) or less according to the Kellgren-Lawrence classification; verified by knee radiograph performed during the last 6 months (Kheshie et al., 2014).
•For bilateral knee osteoarthritis, the most painful knee based on pain score will be taken for evaluation; whereas, if findings were identical, the dominant side of the knee would be included (Yurtkuran et al., 2007, Kheshie et al., 2014)

•The exclusion criteria will be as follows: (1) severe knee osteoarthritis (grade 4) according to the Kellgren-Lawrence classification, (2) other pathological conditions such as rheumatic disease, previous hip or knee joint replacement, congenital dysplasia, osteochondritis dissecans, intra-articular fractures, septic arthritis, Perthes disease, ligament or meniscus injury and plica syndrome, (3) history of acute traumatic injuries to the knee or lower extremities (Nazari et al., 2019), (4) patients who had received intra-articular injections (e.g., corticosteroid, hyaluronic acid, or blood-derived products) for knee osteoarthritis during the last 6 months (Kheshie et al., 2014, Alayat et al., 2017, Nazari et al., 2019), (5) uncontrolled medical conditions (e.g., heart, blood, or respiratory disease) that would limit participation with the assessments and intervention program (Alayat et al., 2017), and (6) current participation in another knee osteoarthritis-related interventional study.

发起方

BTL Industries Malaysia Sdn Bhd