ISRCTN11812525已完成2 期
A phase II study of preoperative chemoradiation with UFT-E plus leucovorin and the translational research for detection of predictive markers in the patients with locally advanced resectable rectal cancer
ational Cancer Center0 个研究点目标入组 121 人开始时间: 2016年7月25日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 121
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Histologically diagnosed adenocarcinoma of rectum
- •2. Located within 8cm from anal verge
- •3. cT3/4 by rectal MRI+/- endorectal ultrasound
- •4. 18 years old or more
- •5. ECOG performance status <=2
- •6. No previous chemotherapy
- •7. No previous radiotherapy to pelvis
- •8. Adequate bone marrow, hepatic, and renal function
排除标准
- •1. Rectal cancer of histology other than adenocarcinoma
- •2. Adenocarcinoma developed from inflammatory bowel disease
- •3. Presence of distant metastases
- •4. Existence of unresected synchronous colon cancer
- •5. Unresolved bowel obstruction
- •6. Clinically unresectable disease
- •7. Uncontrolled cardiovascular disease
- •8. Uncontrolled active infection
- •9. History of other malignancies within 5 years from screening
- •10. History of organ transplantation that necessitates immunosuppressive treatment
- •11. Uncontrolled epileptic disease or psychiatric disease
- •12. Pregnant or breastfeeding women, or women with child-bearing potential who are not compliant to 13. Contraception policy of this study
研究者
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