A Phase II trial of preoperative chemoradiation therapy with S-1 for locally-advanced rectal cancer - Preoperative chemoradiation therapy with S-1 for locally-advanced rectal cancer

Department of Surgery, Miyagi Cancer Center0 个研究点目标入组 15 人开始时间: 2014年12月1日最近更新: 2023年10月17日

适应症

试验速览

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•1) Patients with past history of severe drug allergy. 2) Patients with active cancers in other organs or multicentric cancers in colorectum. 3) Contraindication of S-1 administration. 4) Patients who suffered from infection with fever higher than 38 degree. 5) Patients with severe complications such as bowel obstruction, ileus, intestinal pneumonitis or pulmonary fibrosis, uncontrolled diabetes, uncontrolled hypertension, heart failure, renal failure, liver dysfunction and others. 6) Patients with past history of intestinal pneumonitis. 7) Patients with pleural or ascites retention which should be treated. 8) Patients with fresh bleeding from intestinal tract. 9) Patients with watery diarrhea. 10) Women who are willing to pregnancy or possible to be pregnant. Patients who do not intend to prevent pregnancy. 11) Patients who are continuing steroid administration orally or intravenously. 12) Patients with HBs positive. 13) Patients whom doctors consider not to be eligible for this study for some other reasons.

发起方

Department of Surgery, Miyagi Cancer Center