JPRN-UMIN000015530
Completed
N/A
A Phase II trial of preoperative chemoradiation therapy with S-1 for locally-advanced rectal cancer - Preoperative chemoradiation therapy with S-1 for locally-advanced rectal cancer
Department of Surgery, Miyagi Cancer Center0 sites15 target enrollmentDecember 1, 2014
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- locally advanced rectal cancer (T3-4, N0-2, M0)
- Sponsor
- Department of Surgery, Miyagi Cancer Center
- Enrollment
- 15
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1\) Patients with past history of severe drug allergy. 2\) Patients with active cancers in other organs or multicentric cancers in colorectum. 3\) Contraindication of S\-1 administration. 4\) Patients who suffered from infection with fever higher than 38 degree. 5\) Patients with severe complications such as bowel obstruction, ileus, intestinal pneumonitis or pulmonary fibrosis, uncontrolled diabetes, uncontrolled hypertension, heart failure, renal failure, liver dysfunction and others. 6\) Patients with past history of intestinal pneumonitis. 7\) Patients with pleural or ascites retention which should be treated. 8\) Patients with fresh bleeding from intestinal tract. 9\) Patients with watery diarrhea. 10\) Women who are willing to pregnancy or possible to be pregnant. Patients who do not intend to prevent pregnancy. 11\) Patients who are continuing steroid administration orally or intravenously. 12\) Patients with HBs positive. 13\) Patients whom doctors consider not to be eligible for this study for some other reasons.
Outcomes
Primary Outcomes
Not specified
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