NL-OMON37548
Completed
Not Applicable
Assessing brain hemodynamics using Arterial Spin Labeling. - A-CO2
niversitair Medisch Centrum Utrecht0 sites180 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cerebrovascular disease
- Sponsor
- niversitair Medisch Centrum Utrecht
- Enrollment
- 180
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Inclusion criteria for the healthy volunteers:
- •\- 18 years or older
- •\- male or female
- •\- informed consent after extensive explanation about the device and the research protocol
- •\- healthy;Inclusion criteria for patients:
- •\- 18 years or older
- •\- male or female
- •\- (A)symptomatic extracranial vascular disease (stenosis of 70\-100%)
- •Symptomatic middle cerebral artery occlusion
- •\- Informed consent after extensive explanation about the device and the research protocol
Exclusion Criteria
- •Exclusion criteria for the healthy volunteers:
- •\- Contraindications for MRI (claustrophobia, or standard MRI contraindications such as pacemakers or specific metal objects in or around the body)
- •\- Previous history of ischemic symptoms
- •\- Minors or (legally) incompetent adults;Exclusion criteria for patients:
- •\- Contraindications for MRI (claustrophobia, or standard MRI contraindications such as pacemakers or specific metal objects in or around the body)
- •\- Unwilling or unable to co\-operate with breathing manoeuvres
- •\- Known cardiac or pulmonary disease
- •\- altered consciousness
- •\- Non compliance with prescribed anti\-seizure medication
- •\- Minors or (legally) incompetent adults
Outcomes
Primary Outcomes
Not specified
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