Cerebral perfusion, measured by Arterial Spin Labeling (ASL) perfusion MRI, in relation to outcome in children and young adults with ischaemic stroke - Brain perfusion in relation to outcome in young stroke patients

niversitair Medisch Centrum Utrecht0 个研究点目标入组 80 人开始时间: 待定最近更新: 2024年5月13日

适应症

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•For patients in the retrospective cohort:
•- Children at the age of 7 years - 18 years and adults between 18 and 50 years of age
•- Patients can undergo MR imaging on the 3 Tesla MR scanner without the necessity for anaesthesia (children > 6 years of age)
•- Patients treated in the UMC Utrecht for arterial ischaemic stroke in the anterior cerebral circulation between January 2000 and August 2007
•- Proven non-atherosclerotic arteriopathy at vascular imaging < 3 months after the onset of symptoms
•- Informed consent must be given by the patient and/or parents.;For patients in the prospective cohort:
•- Children at the age of 1 month - 18 years and adults between 18 and 50 years of age
•- Patients are able to undergo MR investigation within 72 hours after the onset of symptoms and after 6 and 12 months
•- Arterial ischaemic stroke (AIS) in the anterior cerebral circulation
•- The cause of stroke is an underlying non-atherosclerotic arteriopathy
•- Informed consent must be given by the patient and/or parents.

•Contra-indications for MRI
•(claustrophobia; pacemaker or automatic defibrillator; some mechanical heart valves; swan-ganz catheter; some aneurysm clips; gastrointestinal clips; cochlear implant; metal object in eye; dental prosthesis with magnetic attachment; hip prosthesis and metal hipnails of more than 50 cm; hydrocephalus- or insulinpump; uncovered skin; medicine patch; piercing)

发起方

niversitair Medisch Centrum Utrecht