Prevention of Shivering Associated With Spinal Anesthesia

Phase 2

Not yet recruiting

• Conditions: Shivering, Spinal Anesthesia
• Interventions: Drug: Dexmedetomidine; Drug: Ketamine; Drug: Meperidine

• Registration Number: NCT06082076
• Lead Sponsor: Assiut University

Brief Summary

The aim of the study is to compare the effectiveness of prophylactic use of intravenous (IV) dexmedetomidine VS ketamine and meperidine(as a control group) in prevention of shivering associated with intrathecal anesthesia in patients undergoing knee arthroscopy

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-10
• Study First Submitted: 2023-10-08
• Study First Submitted QC: 2023-10-08
• Last Update Submitted: 2023-10-08
• Study First Posted: 2023-10-13
• Last Update Posted: 2023-10-13
• Study Start: 2023-11
• Primary Completion: 2024-11
• Study Completion: 2024-12

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• BMI 20-30 Scheduled patients for knee arthroscopy under spinal anesthesia. American Society of Anesthesiologists (ASA) physical status: I and II

Exclusion Criteria

• Patient refusal Aged less than 18 years or lesser than 150 cm in height Pregnant woman Allergy to the studied drugs. Patients with contraindications to spinal anesthesia. Patients with advanced decompensated cardiac, respiratory,renal or hepatic diseases, ASA III-IV Coagulopathy or thrombocytopenia CNS diseases as epilepsy, stroke or psychiatric illness.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
Group D (dexmedetomidine group)	Dexmedetomidine	-
Group K (ketamine group)	Ketamine	-
Group C (control group)	Meperidine	-

Primary Outcome Measures

Name	Time	Method
Incidence of shivering	During operation time	Incidence of shivering post intrathecal anesthesia is recorded