临床试验/NCT06082076

NCT06082076尚未招募2 期

Dexmedetomidine Versus Ketamine to Prevent Shivering Associated With Intrathecal Anesthesia in Patients Undergoing Knee Arthroscopy:A Randomized, Controlled Double Blinded Study.

Assiut University0 个研究点目标入组 90 人开始时间: 2023年11月最近更新: 2023年10月13日

适应症

干预措施

试验速览

阶段: 2 期
状态: 尚未招募
发起方: Assiut University
入组人数: 90
主要终点: Incidence of shivering

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者记录与标识符相似试验

研究概览

简要总结

The aim of the study is to compare the effectiveness of prophylactic use of intravenous (IV) dexmedetomidine VS ketamine and meperidine(as a control group) in prevention of shivering associated with intrathecal anesthesia in patients undergoing knee arthroscopy

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Factorial
主要目的: Treatment
盲法: Triple (Participant, Care Provider, Outcomes Assessor)

入排标准

年龄范围: 18 Years 至 60 Years（Adult）
性别: All
接受健康志愿者: 是

入选标准

•BMI 20-30 Scheduled patients for knee arthroscopy under spinal anesthesia. American Society of Anesthesiologists (ASA) physical status: I and II

排除标准

•Patient refusal Aged less than 18 years or lesser than 150 cm in height Pregnant woman Allergy to the studied drugs. Patients with contraindications to spinal anesthesia. Patients with advanced decompensated cardiac, respiratory,renal or hepatic diseases, ASA III-IV Coagulopathy or thrombocytopenia CNS diseases as epilepsy, stroke or psychiatric illness.

研究组 & 干预措施

Group D (dexmedetomidine group)

Active Comparator

干预措施: Dexmedetomidine (Drug)

Group K (ketamine group)

Active Comparator

干预措施: Ketamine (Drug)

Group C (control group)

Placebo Comparator

干预措施: Meperidine (Drug)

结局指标

主要结局

Incidence of shivering

时间窗: During operation time

Incidence of shivering post intrathecal anesthesia is recorded

次要结局

未报告次要终点

研究者

发起方

Assiut University

申办方类型

Other

责任方

Principal Investigator

主要研究者

Ahmed Galal Mohammed Mohammed

Mohammed Mohammed

Assiut University

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