NL-OMON40863已完成不适用
Day-night rhythm in human skeletal muscle metabolism - Day-night Rhythm in Human Skeletal Muscle
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 26
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Caucasian
- •Healthy (as determined by dependent physician based on medical questionnaire)
- •Age: 18-35 years
- •Normal BMI (18-25 kg/m2)
- •Regular sleeping time (normally 7-9h daily)
排除标准
- •Extreme early bird or extreme night person (score <=30 or >=70 on MEQ-SA questionnaire)
- •Heavily varying sleep-wake rhythm
- •Shiftwork during last 3 months
- •Travel across >1 time zone in the last 3 months
- •Engagement in exercise > 2 hours total per week
- •Using >400mg caffeine daily (more than 4 coffee or energy drink)
- •Unstable body weight (weight gain or loss > 3kg in the last 3 months)
- •Significant food allergies/intolerance (seriously hampering study meals)
- •Participation in another biomedical study within 1 month before the first study visit;• Any contra-indication to Magnetic Resonance Imaging (MRI) scanning:
- •o Any implant or prosthesis that is contra-indicated for MRI
- •o Metal containing foreign bodies in the eye or brain
- •o Any other metal containing objects contra-indicated for MRI scanning
- •o Claustrophobia
- •o Epilepsy;• Any contra-indication to the CorTemp telemetric pill:
- •o Known or suspected obstructive disease of the gastrointestinal tract
- •o History of disorders or impairment of the gag reflex
- •o Previous gastrointestinal surgery
- •o Felinization of the esophagus
- •o Hypomotility disorders of the gastro-intestinal tract
- •o Implanted electromedical device;• Previous allergic reaction to Tegaderm hypoallergenic medical adhesive covering.
- •Any acute condition, exacerbation of chronic condition, or medical history that would in the investigator*s opinion interfere with the study
研究者
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