Analysis of Biomarkers in Lymph Node Tissue

Active, not recruiting

• Conditions: Analysis of Biomarkers in Lymph Node Tissue

• Registration Number: NCT04228796
• Lead Sponsor: Mayo Clinic

Brief Summary

Researchers are doing an exploratory analysis of biomarkers to correlate with treatment outcome of transplant surgery.

Detailed Description

Researchers will study previously collected tissue, which was sent for pathological examination, of 200 patients who underwent transplant surgery. Concentration of biomarkers in lymph node tissue will be measured.

Study Timeline

• Study Start: 2020-01-06
• Study First Submitted: 2020-01-11
• Study First Submitted QC: 2020-01-11
• Study First Posted: 2020-01-14
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-31
• Last Update Posted: 2025-04-01
• Primary Completion: 2026-01
• Study Completion: 2027-01

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Adults (18+years of age)
• Undergo any organ transplant

Exclusion Criteria

• Under the age of 18 years old

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
List of biomarkers	Baseline	Immunohistochemistry (IHC) for the LYVE1, VEGFR3 expression, VEGF-A/C/D, Ki-67, MMP-9 and TIMP-1

Trial Locations

Locations (1)

Mayo Clinic in Florida; 🇺🇸 Jacksonville, Florida, United States