Evaluation of Home Blood Pressure Measurement for the Management of Hypertension in Treated Hypertensive Patients
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 701
- 试验地点
- 1
- 主要终点
- Difference of 24-hour blood pressure control rate
研究概览
简要总结
Home blood pressure measurement has been reported to be associated with better clinic blood pressure and daytime blood pressure control. However, no study has evaluated the association between home blood pressure measurement and control of 24-hour ambulatory blood pressure in real world practice.
The purpose of the present study is to investigate the effect of home blood pressure measurement on the control of ambulatory blood pressure in the real world.
The detailed purposes of the present study are (1) to investigate the effects of home blood pressure measurement on the appropriate control of 24-hour ambulatory blood pressure in hypertensive patients treated with antihypertensive drug, (2) to evaluate the effect of home blood pressure measurement on the occurrence of cardiovascular events and target organ damage, (3) to investigate the status and appropriateness of home blood pressure measurement in the real world, and (4) to investigate factors of home blood pressure measurement methods affecting the treatment of hypertension.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with hypertension and taking antihypertensive drugs more than 1 year
排除标准
- •Secondary hypertension
- •Hypertensive emergency and urgency
- •Severe heart failure (NYHA III and IV)
- •Angina with 6 months
- •Myocardial infarction within 6 months
- •Peripheral artery disease within 6 months
- •Significant arrhythmia (i.e. ventricular tachycardia and fibrillation, atrial fibrillation, atrial flutter)
- •Pregnancy
- •Night labor, shift worker
- •Those who are currently participating in other clinical studies
- •Those who have taken other clinical trial drugs within the past month
- •According to the opinion of the researcher, those who have or may have a disease that may interfere with the completion of the study
- •History of drug or alcohol dependence within 6 months
结局指标
主要结局
Difference of 24-hour blood pressure control rate
时间窗: at baseline and 3 years of follow up
difference of 24-hour blood pressure control rate between patients who measure and do not measure home blood pressure
次要结局
- Difference of daytime blood pressure control rate(at baseline and 3 years of follow up)
- Difference of office blood pressure control rate(at baseline and 3 years of follow up)
- Difference of systolic and diastolic blood pressure (office, 24-hour, daytime, nighttime)(at baseline and 3 years of follow up)
- Rate of home blood pressure measurement(at baseline and 3 years of follow up)
- Reflection of home blood pressure(at baseline and 3 years of follow up)
- cardiovascular disease prevalence and target organ damage(at baseline and 3 years of follow up)
- Changes of home blood pressure measurement rate(from baseline to 3 years of follow up)
- Cardiovascular disease events and target organ damage(during 3 years of follow up from baseline measurement)
研究者
Moo-Yong Rhee
Professor
DongGuk University