To study the mutation profile of right versus left sided colon cancer

Not Applicable

• Conditions: Health Condition 1: C15-C26- Malignant neoplasms of digestive organs

• Registration Number: CTRI/2024/04/065230
• Lead Sponsor: A

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1. Patients aged = 18 to 75 years,

2. Patients of either gender,

3. Patients with metastatic colon cancer confirmed on histology with a colon biopsy at time

of colonoscopy

4. Patients planned for upfront systemic therapy.

5. Patients with Karnofsky performance status 70% or higher and adequate hematological

and end-organ function

6. Availability of sufficient tumor tissue to carry out mutational profiling.

7. Patients willing to participate in the study and sign an informed consent form.

Exclusion Criteria

1. Patients with recurrent colon cancer

2. Patients with previously treated other malignancies or who have received previous

systemic treatment

3. Patients with any underlying hereditary syndromes

4. Pregnant women;

5. Patients who refuse to give consent.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The differences in incidence of mutation in left versus right sided colon <br/ ><br>cancer would reflect different biological characteristics of proximal and distal colon cells <br/ ><br>which in turn determine different responses to treatmentTimepoint: 6 months

Secondary Outcome Measures

Name	Time	Method
ILTimepoint: NI