Prognostic Significance of COVID-19 MSCT Chest Findings on Short Term Disease Progression
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- correlation between initial CT findings with short term clinical outcome
研究概览
简要总结
Background: CT has been used on a massive scale to help identify and investigate suspected or confirmed cases of COVID-19 pneumonia. This study aimed to assess the prognostic significance of the chest findings MSCT of Covid-19 patients and to determine if prognosis can rely on the initial CT imaging. Methods: The study design was retrospective cohort study. It was carried out on 300 patients presented to the chest outpatient clinics in Benha university hospitals and Elabbasyia chest hospital with clinical picture suggestive of COVID 19 infection. The CT finding were then compared to the short-term clinical outcome of the patients (1-3weeks), acquired from the hospital patient data archive. According to the progression of the respiratory symptoms (include; dyspnea, respiratory rate and O2 saturation), the short-term clinical outcome of the patients was classified into 4 groups; Group A: (mild cases), Group B: (moderate cases), Group C: (sever cases), and Group D: (fatality cases).
详细描述
Patients and methods The study design was retrospective cohort study. It was carried out on 300 patients presented to the chest outpatient clinics in Benha university hospitals and Elabbasyia chest hospital with clinical picture suggestive of COVID 19 infection during the period from April 2020 to December 2020.
Inclusion criteria:
• Patients who had positive RT-PCR test for COVID-19 infection and show positive chest CT findings.
Exclusion criteria:
- Patients with negative RT PCR test for COVID 19 infection.
- Patients with positive RT PCR test for COVID 19 and negative chest CT findings.
- Patients with other pre-existing lung pathologies in the chest CT.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 20 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who had positive RT-PCR test for COVID-19 infection and show positive chest CT findings.
排除标准
- •Patients with negative RT PCR test for COVID 19 infection.
- •Patients with positive RT PCR test for COVID 19 and negative chest CT findings.
- •Patients with other pre-existing lung pathologies in the chest CT.
结局指标
主要结局
correlation between initial CT findings with short term clinical outcome
时间窗: 3 weeks
The CT finding were then compared to the short-term clinical outcome of the patients (1-3weeks), acquired from the hospital patient data archive; respiratory symptoms (dyspnea, respiratory rate and O2 saturation),
次要结局
未报告次要终点
研究者
AMIRA HUSSEIN ALLAM
assistant professor of chest diseases and tuberculosis
Benha University