The Use of Preoperative CT Chest Scan in the Pre-anesthetic Assessment of COVID-19
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 76
- 试验地点
- 1
- 主要终点
- pneumonia severity.
研究概览
简要总结
The role of CT scan of the chest in Pre-anesthetic assessment of the severity of COVID-19 and the correlations between CT measurements of the aortic and pulmonary arteries diameters and severity of pneumonia.
详细描述
Patients who were scheduled for emergency surgery during COVID-19 pandemic should have be screened for COVID pre-operatively given the prevalence f asymptomatic or mildly symptomatic cases that could be carriers to infection and possibly cause cross infection to the operating room staff especially the anesthetists who deal with the upper airway during intubation with high possibility of getting infected with SARS-COV 2 virus. Waiting respiratory tract PCR (RT-PCR) test for COVID can delay the surgery which may increase patients morbidity and mortality. RT-PCR test has limited sensitivity and specificity.
Patients who are confirmed to have COVID-19 infection (have positive RT-PCR) or patients who have possible COVID-19 infection (have symptoms but were not tested with RT-PCR) will undergo non-enhanced CT scanning of the chest (without giving IV contrast).
Chest CT scan will be interpreted by 2 Consultants radiologists with an experience of at least 10 years in their field.
The radiologists are going to be requested to comment on the lung parenchyma, describing the findings , assess the pulmonary artery, aorta diameters and the aorta:pulmonary diameters ratio will be then calculated. The degree of pneumonia severity index will then be described as well.
The radiologists will be blinded to the aim of the study.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients scheduled for emergency surgery with symptoms suggestive of COVID-19 infection.
排除标准
- •Pregnancy.
- •Haemodynamic instability (Mean arterial blood pressure above 65 mmHg or the need for of inotropic drugs to maintain mean arterial blood pressure above 65 mmHg).
- •Active bleeding.
- •Any indication by the surgeon or the anesthesiologist to proceed for immediate surgery for the patient safety.
- •Patients refusal to do CT scanning.
结局指标
主要结局
pneumonia severity.
时间窗: 90 days
The pneumonia severity will be assessed by the radiologist.
Pulmonary artery diameter TO Aorta diameter ratio
时间窗: 90 days
Pulmonary artery diameter TO Aorta diameter ratio will be calculated
Pulmonary artery diameter
时间窗: 90 days
Pulmonary artery sectional diameter will be calculated by using cursor method on CT scan
Aorta diameter
时间窗: 90 days
Aorta cross sectional diameter will be calculated by using cursor method on CT scan
次要结局
- Description of the lesions found in the CT scan(90 days)
研究者
MOHAMMED FAWZI ALI ABOSAMAK
ICU consultant
Tanta University